Epiretinal Membrane, Retinal Disease
Conditions
Keywords
Internal limiting membrane peeling
Brief summary
The patients who are diagnosed with idiopathic epiretinal membrane and scheduled to undergo epiretinal membrane removal will be treated with conventional vitrectomy and the epiretinal membrane will be removed. After removal of the epiretinal membrane, indocyanine green staining will be used to determine the internal limiting membrane (ILM) peeled off with the epiretinal membrane. (Group 1: spontaneous ILM peeling) If it is confirmed that the internal limiting membrane is not peeled together, the investigators determine whether the active Internal limiting membrane peeling is performed by 1:1 randomization immediately during surgery. (Group 2: Active ILM peeling, Group 3: no ILM peeling) The outcomes of the three groups will be compared.
Interventions
PROCEDUREInternal Limiting Membrane Peeling
After removal of the epiretinal membrane, indocyanine green staining will be used to determine the internal limiting membrane (ILM) peeled off with the epiretinal membrane. (Group 1: spontaneous ILM peeling) If it is confirmed that the internal limiting membrane is not peeled together, the investigators determine whether the active Internal limiting membrane peeling is performed by 1:1 randomization immediately during surgery. (Group 2: Active ILM peeling, Group 3: no ILM peeling) The outcomes of the three groups will be compared.
Sponsors
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age equal to or older than 19 years * Patients diagnosed with idiopathic epiretinal membrane and scheduled to undergo the epiretinal membrane removal surgery
Exclusion criteria
* Accompanied with retinal vascular disease or intraocular inflammation * Prior treatment with vitrectomy in the study eye * History of glaucoma
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Epiretinal membrane recurrence | 12 months after the surgery | Recurrence of the epiretinal membrane after the surgery |
Secondary
| Measure | Time frame |
|---|---|
| Best-corrected visual acuity | 12 months after the surgery |
| M-chart | 12 months after the surgery |
| Aniseikonia | 12 months after the surgery |
Countries
South Korea
Outcome results
None listed