Effects of Corneal Anatomical Match Between Donor and Recipient During DALK Surgery on Final Visual and Refractive Outcomes in Patients With KCN

Effects of Corneal Anatomical Match Between Donor and Recipient During DALK Surgery on Final Visual and Refractive Outcomes in Patients With KCN: a Clinical Trial

Status

UNKNOWN

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04130334

Enrollment

Registered

2019-10-17

Start date

2018-06-01

Completion date

2020-03-01

Last updated

2019-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Keratoconus

Brief summary

Patients with KCN who undergo cornea transplantation divided to 2 groups: Group1: After mechanical trephination, horizontal meridian of donor's cornea sutured to horizontal meridian of recipient cornea Group 2: After mechanical trephination, horizontal meridian of donor's cornea sutured to vertical meridian of recipient cornea After suture removal, best corrected visual acuity, refractive error, corneal keratometry, irregularity of corneal surface and high order aberration of two groups will compare

Interventions

PROCEDUREAfter mechanical trephination, horizontal meridian of donor's cornea sutured to horizontal meridian of recipient cornea

After mechanical trephination, horizontal meridian of donor's cornea sutured to horizontal meridian of recipient cornea

PROCEDURE: After mechanical trephination, horizontal meridian of donor's cornea sutured to vertical meridian of recipient cornea

: After mechanical trephination, horizontal meridian of donor's cornea sutured to vertical meridian of recipient cornea

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

ALL

Age

15 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Patients with KCN who undergo DALK surgery

Exclusion criteria

* Penetrating Keratoplasty surgery * Other corneal diseases * dystrophies * Corneal graft rejection

Design outcomes

Primary

Measure	Time frame	Description
Best corrected visual acuity	14 months	Snellen chart
graft astigmatism	14 months	Topography

Countries

Iran

Contacts

Primary ContactSepehr Feizi, MD

labbafi@hotmail.com009822591616

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026