Predictive Factors for a Successful Return to Run After ACL-R

Predictive Factors for a Successful Return to Run After Anterior Cruciate Ligament Reconstruction and Underlying Bio-mechanical Factors

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04130308

Enrollment

Registered

2019-10-17

Start date

2018-01-10

Completion date

2019-04-30

Last updated

2019-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION

Brief summary

After anterior cruciate ligament (LCA) rupture, the recommended treatment for athletes is the surgical reconstruction of the ligament (ACL-R), followed by a long rehabilitation period. The results of this treatment are sub-optimal with a low rate of return to pre-injury level of sport, a high risk of reinjury and early knee osteoarthritis. To improve treatment outcomes, researchers and clinicians recommend optimizing rehabilitation protocols. They recommend individualizing rehabilitation progression based on objective criteria. However, current defined criteria relied on experts' opinions and not scientific validation. Return to run after ACL reconstruction is an important rehabilitation milestone. It often means the beginning of the return to sport continuum. A successful return to run is therefore crucial for both the patient and clinician. In this study, the investigators aim to determine the predictive outcomes for a successful return to run after ACL-R.

Interventions

OTHERRetrun to run protocol

Progressive return to run protocol for patients after ACL-R

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

Experimental group Inclusion Criteria: * ACL-R 3 to 4 months ago

Exclusion criteria

* already returned to run * multiple ligament lesions Control group Inclusion Criteria: \- healthy person

Design outcomes

Primary

Measure	Time frame	Description
Self-reported outcomes: IKDC	Day 0	IKDC: 0-100
Modified Y-balance test	Day 0	Modified Y-balance test (m)
step-down test	Day 0	endurance test, number of repetition
Self-reported outcomes: ACL-RSI	Day 0	ACL-RSI: 0-100
Muscular strength assessment	Day 0	Quadriceps, hamstring and gluteus strength assessment with handheld dynamometer (N)

Secondary

Measure	Time frame	Description
Running kinetic	Day 0 and Day 14	kinetic (N)
Knee joint contact force	Day 0 and Day 14	knee joint contact force (N)
Running kinematic	Day 0 and Day 14	knee kinematic (degree)

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026