Bladder Perforation Post-TURBT: Definition, Incidence and Natural HistoryStudy

Bladder Perforation Post-TURBT: Definition, Incidence and Natural History. A Prospective Cohort Study

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04129606

Acronym

TURBT-BP

Enrollment

300

Registered

2019-10-17

Start date

2019-07-01

Completion date

2021-07-01

Last updated

2019-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder Cancer, Bladder Urothelial Carcinoma, Injuries, Perforation of Bladder, Recurrence Tumor, Resection Margin, Seeding, Neoplasm, Trauma

Keywords

Perforation of Bladder, Bladder Cancer, Resection Margin

Brief summary

In view of sparse data of precise definition, risk factors, natural history and management of bladder perforation following Transurethral resection of bladder tumour (TURBT). We aim to correlate the relation between the site, depth and extent of resection with bladder perforation. Also, correlation between vertical depth, horizontal extent of resection and recurrence and progression of tumor

Interventions

DIAGNOSTIC_TESTComputed tomographic cystography

CT cystogram performed after the procedure by the injection of 400mL of 1/4 saline-diluted contrast solution (meglumine ioxitalamate) with low-pressure infusion (60 cm gravity pressure) through the Foley catheter.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* papillary bladder tumor (denovo or recurrent) * resectable nodular bladder tumor

Exclusion criteria

* Refuse to complete study requirements * muscle invasive bladder tumor

Design outcomes

Primary

Measure	Time frame	Description
Prevalence of bladder perforation post-Transurethral resection of bladder tumour	24 months	calculate the numbers of bladder perforation diagnosed by CT cystogram divided by the total number of patients

Secondary

Measure	Time frame	Description
Correlation between the cystoscopical and radiological bladder perforation	24 months	compare the numbers of bladder perforation diagnosed by CT cystogram by the number of bladder perforation described by surgeon
assess the recurrence free rate in bladder perforation groups at 2 year follow up	24 months	calculate the number of recurrence pf bladder tumor in bladder perforation at 2 year follow up

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026