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Evaluation of the Hypoalgesic Effects of Transcranial Direct Current (tDCS) in Healthy Subjects

Evaluation of the Hypoalgesic Effects of Transcranial Direct Current (tDCS) in Combination With Motion Representation Tools in Healthy Subjects: a Double-blind Randomized Placebo-controlled Trial.

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04127253
Enrollment
45
Registered
2019-10-15
Start date
2020-01-01
Completion date
2020-07-01
Last updated
2019-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain Modulation

Keywords

Motor imagery, Transcranial direct current stimulation, Action observation

Brief summary

The main objective of this research is to evaluate and quantify hypoalgesic effects caused by imagination and observation with or without the presence of transcranial direct current (tDCS) in healthy participants. The secondary objective of this research is to evaluate the possible relationships between hypoalgesic effects and different physical and cognitive variables such as the ability to generate motor mental images, mental chronometry and levels of physical activity.

Interventions

DEVICESooma transcranial direct current stimulation device plus Brain training tools

This group will carry out an observation training of actions and motor imagery in combination with the stimulation of the transcranial direct current.

DEVICEPlacebo Sooma transcranial direct current stimulation deviceplus Brain training tools

This group will carry out an observation training of actions and motor imagery in combination with the placebo stimulation of the transcranial direct current, where it will be acrtivo during 15 seconds and then it will be turned off during the rest of the intervention.

BEHAVIORALBrain training tools in isolation

This group will act as a control, they will only carry out the training of action observation and motor imagery.

Sponsors

Centro Universitario La Salle
CollaboratorOTHER
Universidad Autonoma de Madrid
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* asymptomatic participants * men and women aged 18 to 65 years

Exclusion criteria

* insomnia * nausea * headache * pregnant woman * use of painkillers in the last twenty four hours * presence of metal inside the head * pacemaker * wound on the area of electrodes' application * drugs consumer * recent application of transcranial direct stimulation * psychiatric disease who lead the subject to a misunderstand of the study

Design outcomes

Primary

MeasureTime frameDescription
Pressure pain thresholdChange in Pressure pain threshold just before the start of the intervention, immediately at the end of the intervention and 15 minutes after the end of the interventionPressure pain threshold has been defined as the minimal amount of pressure at which a sense of pressure first changes to pain or discomfort

Secondary

MeasureTime frameDescription
Ability to generate motor imagesJust before the start of the interventionThe ability to generate motor images will be measured through The movement imagery questionnaire-revised (MIQ-R) is an 8-item self-report inventory that was used to assess visual and kinesthetic motor imagery ability. Four different movements are included in the MIQ-R, which is comprised of 4 visual and 4 kinesthetic items. For each item, participants read a description of the movement. They then physically performed the movement and were instructed to reassume the starting position after finishing the movement and before performing the mental task, imagining the movement visually or kinesthetically. Each participant then rated the ease or difficulty of mentally generating that image on a 7-point scale, in which 7 indicates very easy to see/feel and 1 very difficult to see/feel. The internal consistencies of the MIQ-R have been consistently adequate.
Mental ChronometryJust before the start of the interventionMental chronometry is a reliable measure that has been widely used to record objective measurements of the ability to create mental motor images
The degree of physical activityJust before the start of the interventionThe level of physical activity will be assessed using the International Physical Activity Questionnaire, which allows the participants to be divided into 3 groups according to their level of activity, which can be high, moderate, and low or inactive

Countries

Spain

Contacts

Primary ContactRoy A La Tocuhe, physiotherapist PhD
roylatouche@lasallecamous.es917401980

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026