Association of Hypertensive Disorder of Pregnancy With Sleep-disordered Breathing.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04126629

Enrollment

100

Registered

2019-10-15

Start date

2020-01-22

Completion date

2021-09-01

Last updated

2020-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertensive Disorder of Pregnancy, Sleep-disordered Breathing

Keywords

Hypertensive Disorder of Pregnancy, Sleep-disordered Breathing, HDP, SDB

Brief summary

This study aims to assess the prevalence of sleep disorder breathing in pregnant women with a singleton gestation who develop hypertensive disorder of pregnancy (HDP) compared to women without HDP, when matched for gestational age and body mass index.

Detailed description

Sleeping disorder breathing is not only underdiagnosed in the general population, but more specifically in pregnant women. Some recent research has found an association between sleep disorder breathing and preeclampsia. Both conditions have shown to be associated with worse pregnancy outcomes. Therefore, more research is needed to find the strength of these associations. By gathering more information, this provides investigators with an opportunity to see if there is a way to slow the progression of complications in preeclampsia through the management of sleep-disordered breathing. Preeclampsia continues to be one of the top reasons for maternal mortality in the U.S. and this percentage continues to grow each year. Through the study, investigators hope to bring awareness of the comorbidity and how its similar pathogenesis can potential exacerbate complications in pregnant women.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Inclusion criteria

* 1\. Subject who is capable of consenting in English * 2.Women with a diagnosis of a hypertensive disorder of pregnancy * 3.Greater than 20 weeks pregnant * 4.Singleton fetus * 5.Inpatient

Exclusion criteria

* 1.With acute respiratory distress, including asthma * 2.With micrognathia and other severe craniofacial abnormalities * 3.Active heart failure * 4.Sepsis * 5.Subjects in labor.

Design outcomes

Primary

Measure	Time frame
Prevalence of SDB in women with HDP compared to normotensive women.	03/01/2019-03/01/2021

Countries

United States

Contacts

Primary ContactElena Safronova, MD

safronova-elena@cooperhealth.edu856-968-7547

Outcome results