Acute Coronary Syndrome
Conditions
Brief summary
To determine the effect of intervention of ambient air pollution on acute coronary syndrome patients.
Detailed description
To investgate the effect of wearing facemasks to decreasing levels of exposure to ambient air on acute coronary syndrome patients.
Interventions
DEVICEmask
facemask
Sponsors
Peking University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
1. Non-smoker of any type during past six months and living in a non-smoking household. 2. A diagnosis of myocardial infarction or unstable angina 7-90 days prior to signed informed consent.
Exclusion criteria
1. Unstable CV disorders including uncompensated heart failure, refractory angina, uncontrolled arrhythmias, critical valvular heart disease and severe hypertension. 2. A history of infection with human immunodeficiency virus. 3. History of malignancy including leukemia and lymphoma AND/OR any severe, life-threatening disease AND/OR history of drug abuse within the last 2 years. 4. Pregnancy or intent to get pregnant during the study period.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| vascular function | six months | Systolic blood pressure and diastolic blood pressure measured by omron HBP-1300 |
| autonomic nervous function | six months | Twenty four-hour electrocardiograms and heart rate variability |
Countries
China
Contacts
Primary ContactWei Huang, PhD
Outcome results
None listed