Pain
Conditions
Brief summary
Diclofenac is a proven, commonly prescribed nonsteroidal anti-inflammatory drug (NSAID) that has analgesic, anti-inflammatory, and antipyretic properties, and has been shown to be effective in treating a variety of acute and chronic pain and inflammatory conditions.
Detailed description
Diclofenac is a proven, commonly prescribed nonsteroidal anti-inflammatory drug (NSAID) that has analgesic, anti-inflammatory, and antipyretic properties, and has been shown to be effective in treating a variety of acute and chronic pain and inflammatory conditions. . As with all NSAIDs, diclofenac exerts its action via inhibition of prostaglandin synthesis by inhibiting cyclooxygenase-1 (COX-1)
Interventions
DIAGNOSTIC_TESTDiclofenac + HBB with hysteroscopy
Giving Diclofenac + HBB with hysteroscopy
DIAGNOSTIC_TESTDiclofenav + placebo
Giving Diclofenac + placebo with hysteroscopy
Sponsors
Cairo University
Aljazeera Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* 1\. Patients indicated for diagnostic hysteroscopy including infertility, bleeding, suspected intrauterine pathologies (eg polypi , septea) 2. Reproductive age 20 - 40yrs
Exclusion criteria
* 1\. Menopausal and amenorrhic patients 2. Contraindication to office hysteroscopy such as:- pelvic inflammatory disease, marked cervical stenosis, pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The number of women who will not feel pain | within half an hour | the effect of medications on pain sensation |
Countries
Egypt
Outcome results
None listed