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Atrificial Shrinkage of Blastocyst Before In Vitro Fertilization

Comparative Study Between Two Techniques for Artificial Shrinkage of Blastocysts Prior to Vitrification: LASER Pulse Versus Micro-needle Technique in Increasing Chemical, Clinical Pregnancy and Live Birth Rates After ICSI

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04125017
Enrollment
409
Registered
2019-10-14
Start date
2019-01-01
Completion date
2020-02-05
Last updated
2023-10-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Brief summary

Vitrification is a modern cryopreservation technique based on sudden cooling of reproductive cells to a temperature of -196 ° C in seconds that produces glass-like solidification of a solution without crystallization, but by extreme elevation in viscosity during freezing

Detailed description

Vitrification is a modern cryopreservation technique based on sudden cooling of reproductive cells to a temperature of -196 ° C in seconds that produces glass-like solidification of a solution without crystallization, but by extreme elevation in viscosity during freezing Unlike the slow freezing method, vitrification has better results in a complete elimination of ice crystal inside the cells as well as in the surrounding solution -Also, it has a significantly higher post-thawing survival rate in comparison to slow freezing method

Interventions

DEVICEICSI with laser pulse

Using laser pulse before ICSI

DEVICEICSI with micro needle technique

Using micro needle technique before ICSI

Sponsors

Adam International Hospital
CollaboratorOTHER
Aljazeera Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Intervention model description

effect of using LASER pulse versus micro-needle use in the artificial shrinkage of blastocysts .

Eligibility

Sex/Gender
FEMALE
Age
20 Years to 44 Years
Healthy volunteers
No

Inclusion criteria

* women with infertility from 20 to 44 years

Exclusion criteria

* women with age more than 44 or less than 20

Design outcomes

Primary

MeasureTime frameDescription
The number of women who will have positive pregnancy test2 monthsThe number of women who will come pregnant after each technique

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 16, 2026