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Stopping Cardiovascular Treatments and Mortality in a MICU

Impact on Mortality of Cardiovascular Treatments Interruption in a Medical Intensive Care Unit

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04121429
Acronym
TRAM
Enrollment
150
Registered
2019-10-09
Start date
2019-05-02
Completion date
2019-11-02
Last updated
2019-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Diseases, Critical Care, Medication, Outcome, Fatal

Brief summary

Cardiovascular treatments should not be interrupted following hospital admission, in order to decrease patients' morbidity. However, following ICU admission, such treatments are frequently interrupted and/or modified. The question of the study is to investigate wether such treatment interruption might be responsible for prognosis modifications.

Detailed description

Cardiovascular treatments should not be interrupted following hospital admission, in order to decrease patients' morbidity. However, following ICU admission, such treatments are frequently interrupted and/or modified. Few studies have investigated the outcome impact of medications interruption and/or modifications following hospital admission. We did consider that it might be interesting to study whether treatment continuation, interruption, and/or re-introduction following ICU admission may modify patients' outcome either in the ICU or following hospital discharge (at 3,6 and 12 months).

Interventions

OTHERObservation

No intervention will be performed

Sponsors

University Hospital, Brest
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
15 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* All patients with cardiovascular treatment prior to ICU admission

Exclusion criteria

* Data unavailability * Consent withdrawal following information

Design outcomes

Primary

MeasureTime frameDescription
ICU Mortality2 months following ICU DischargePatients mortality will be assessed at the end of the ICU stay (two months)

Secondary

MeasureTime frameDescription
Hospital mortality2 months following Hospital DischargePatients mortality will be assessed at the end of the hospitalisation stay (two months)
Mortality at Month 3 following discharge3-months following discharge
Mortality at Month 6 following discharge6-months following discharge
Mortality at Month 12 (1-year) following discharge12-months following discharge

Countries

France

Contacts

Primary ContactErwan L'HERr
erwan.lher@chu-brest.fr+33298347181
Backup ContactMargot GICQUEL
+33298347181

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026