Effect of Inspiratory Muscle Training During PR on Dyspnoea and Exercise Tolerance in COPD Patients

Effect of Inspiratory Muscle Training During PR on Dyspnoea and Exercise Tolerance in Chronic Obstructive (COPD)

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04120142

Enrollment

Registered

2019-10-09

Start date

2019-02-01

Completion date

2019-12-01

Last updated

2020-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease

Keywords

COPD, IMT, 6MWT, Dyspoea, SGRQ

Brief summary

Chronic obstructive pulmonary disease is a respiratory disease that results in progressive airflow limitation and respiratory distress. The benefit of inspiratory muscle training (IMT) combined with a pulmonary rehabilitation programme is uncertain. The investigators aimed to demonstrate that, in patients with obstructive pulmonary disease, IMT performed during a PRP is associated with an improvement of dyspnoea and exercise tolerance.

Detailed description

The purpose of this study is to evaluate the effect of the inspiratory muscle training (with incremental load every two weeks in two months) performed during pulmonary rehabilitation on dyspnoea, 6 minutes walk test and quality of life using the St George's respiratory questionnaire (SGRQ) in COPD patients.

Interventions

OTHERPulmonary rehabilitation+IMT

The experimental group receives inspiratory muscle training and aerobic exercise.

OTHERPulmonary rehabilitation

The Active Comparator group received only aerobic exercise.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Caregiver)

Eligibility

Sex/Gender

MALE

Age

45 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Were COPD diagnosed by pulmonary function testing * Clinically stable * Abscence of other obstructive diseases * Signed written consert

Exclusion criteria

* Were previous pneumonectomy or lobectomy in the past 6 months * spontaneous risk of pneumothorax or rib fracture * Incapacity to follow a standard rehabilitation programme (locomotor deficits, acute cardiac failure and acute exacerbation of COPD at the beginning of the programme) * The absence of written informed consent.

Design outcomes

Primary

Measure	Time frame	Description
Dyspnoea	Baseline, After 2 months	The dyspnoea were measured before and after the 6 minutes walk test
Inspiratory muscle strength	Baseline, After 2 months	The inspiratory muscle strength were measured by maximal inspiratory pressure test

Countries

Tunisia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026