Metabolic Syndrome
Conditions
Keywords
Glucose control, Cardiovascular disease risk factors, Sugary beverages, Pulmonary function
Brief summary
Our goal is to determine how the addition of sugar-sweetened beverages to the diet affects glucose control, cardiovascular disease risk factors, and pulmonary function in healthy, young adults.
Detailed description
In a 3-arm randomized controlled trial, 36 participants consumed one of three beverages for three weeks: water (W), caffeine-free soda (S), or 100% fruit juice (FJ). Participants consumed two servings/day (\ 710mL) of their randomized beverage for three weeks, along with their habitual diets. At baseline and following the 3-week intervention, participants completed glucose control, cardiovascular disease risk factor, and pulmonary function assessments.
Interventions
DIETARY_SUPPLEMENTSugary beverage: Fruit juice
Participants consumed 100% fruit juice (\ 710mL) daily for three weeks, along with their habitual diets.
DIETARY_SUPPLEMENTSugary beverage: Soda
Participants consumed soda (\ 710mL) daily for three weeks, along with their habitual diets.
DIETARY_SUPPLEMENTControl: Water
Participants consumed water (\ 710mL) daily for three weeks, along with their habitual diets.
Sponsors
Kansas State University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Free from diagnosis of diabetes and pulmonary illness * Have no intake of glucose or lipid lowering medication.
Exclusion criteria
* Smoke * Currently pregnant * Have bronchitis * Have more than 2 risk factors for cardiovascular disease, as defined by the American College of Sports Medicine (ACSM).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in glucose iAUC | Week 0 and Week 3 | Glucose obtained from blood sample in a fasted state and in response to a meal |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in homeostatic model assessment for insulin resistance | Week 0 and Week 3 | Calculated from fasting glucose and insulin values |
| Change in blood pressure | Week 0 and Week 3 | Evaluated via automated sphygmomanometer. |
| Change in BMI | Week 0 and Week 3 | Weight and height will be combined to report BMI in kg/m\^2 |
| Change in plasma lipids | Week 0 and Week 3 | Total cholesterol (TC), LDL-c , VLDL-c, HDL-c , triglycerides (TG) from blood sample in a fasted state and following consumption of a meal |
| Change in insulin iAUC | Week 0 and Week 3 | Glucose obtained from blood sample in a fasted state and in response to a meal |
| Change in serum fructosamine | Week 0 and Week 3 | Fructosamine obtained from blood sample |
| Change in pulmonary function | Week 0 and Week 3 | Assessed using the maximum flow-volume loop |
Countries
United States
Outcome results
None listed