Risk Factors for Thrombosis in Children With Central Venous Lines

Analysis of Laboratory Markers to Predict Risk of Catheter Related Thrombosis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04117217

Enrollment

200

Registered

2019-10-07

Start date

2017-03-01

Completion date

2021-12-31

Last updated

2024-11-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric Venous Thromboembolism

Brief summary

This project addresses the role of lab markers around the time of central line placement in predicting risk of thrombosis in pediatric patients with central venous lines being placed. The project proposes an innovative way to predict higher risk of thrombosis in the pediatric population to give clinicians a valid tool to guide clinical practice for these patients.

Interventions

DIAGNOSTIC_TESTLabs drawn

We will collect blood samples/biomarkers at the time of enrollment.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

6 Months to 17 Years

Healthy volunteers

Inclusion criteria

* Patients over 5 kg and less than 18 years of age. * Patients having a central venous catheter or cardiac catheterization performed

Exclusion criteria

* prior history of thrombosis * patients with hemophilia A or B

Design outcomes

Primary

Measure	Time frame	Description
Thrombosis	within one year of enrollment	Patients will be enrolled during the time of central line placements and labs would be drawn during line placement. Patients will be followed prospectively for a catheter related t thrombosis event or not. Lab markers and clinical states of patients who develop or do not develop a thrombosis will be analyzed

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026