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Lung Ultrasonography After Laparoscopic Gynecologic Surgery

Lung Ultrasonography for the Assessment of Perioperative Atelectasis After Laparoscopic Gynecologic Oncologic Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04116567
Acronym
LUS-LPS
Enrollment
80
Registered
2019-10-04
Start date
2018-10-03
Completion date
2019-06-28
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Atelectasis

Keywords

Pulmonary Atelectasis, Lung Ultrasound, Laparoscopic Surgery

Brief summary

This study evaluates the influence of surgical and anesthesia-related variable on atelectasis formation during laparoscopic gynecologic oncologic surgery by lung ultrasound.

Detailed description

Approximately 50% of patients undergoing general anesthesia are hypoxemic. Anaesthesia, paralysis, high concentrations of oxygen, inadequate level of PEEP, capnoperitoneum, Trendelenburg position all result in persistent atelectasis. Lung ultrasound is a safe and accurate bedside tool useful to study lung aeration. The aim of the investigator's study was to assess the impact of general anesthesia and laparoscopic gynecologic oncologic surgery on post-operative atelectasis and related oxygenation changes using lung ultrasound.

Interventions

None listed

Sponsors

SONNINO CHIARA
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients older than 18 yo undergoing laparoscopic surgery for gynecologic surgery who provide written informed consent.

Exclusion criteria

* age \< 18 yo; * pregnancy; * refused to partecipate; * known pulmonary metastasis; * preexisting pulmonary conditions (COPD, pleural effusion, pulmonary consolidations, lung edema, pulmonary embolism); * anesthesia with mechanical ventilation in the 2 weeks.

Design outcomes

Primary

MeasureTime frameDescription
Assess if LUS score measured after surgery is higher that LUS score measured before induction of anesthesiaThe outcome will be measured 10 minutes after extubationEach lung will be divided in 6 areas and a score from 0 to 3 will be assigned to each field depending on the loss of aereation detected by ultrasound. LUS score will range between 0 and 36. Lung ultrasound will be performed before induction of anesthesia and 10 minutes after extubation.
Correlation between the increase of LUS score after surgery and surgical or anesthesia-related variables.The outcome will be measured 10 minutes after extubationLogistic regression will be applied to consider the correlation between Delta LUS and the following variables: * lenght of surgery * duration of pneumoperitoneum * angle of Trendelenburg potision * duration of mechanical ventilation * intraoperative fluids * duration of apnea from induction to intubation

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026