Evaluation of Discomfort Associated With Scleral Depression During Retina Examinations

Scleral Depression Pain With Schocket Depressor and Cotton Tipped Applicator: Depression Eye Pain Relief Evaluation Study (DEPRESS)

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04115917

Acronym

DEPRESS

Enrollment

Registered

2019-10-04

Start date

2018-01-01

Completion date

2019-01-31

Last updated

2019-10-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Retina--Diseases, Retinal Degeneration, Retinal Detachment

Keywords

Scleral Depression, Visual Analog Scale, Pain, Discomfort, Schocket Scleral Depressor, Cotton Tipped Applicator, Diabetes

Brief summary

Scleral depression is an important technique used to examine the peripheral retina but often causes patient discomfort. The goal of this study was to compare levels of discomfort during scleral depression with a Schocket scleral depressor and cotton tipped applicator.

Interventions

DEVICESchocket scleral depressor

Scleral Depression on eye with Schocket scleral depressor

DEVICECotton tipped applicator

Scleral Depression on eye with cotton tipped applicator

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Intervention model description

The first eye to undergo scleral depression was randomly assigned, then that eye was randomized two either of the scleral depression methods. The contralateral eye then had the alternative method of scleral depression performed.

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Adult patients who received dilated eye examinations in the retina or general eye clinic

Exclusion criteria

* Younger than 18 * Pregnant * Prior scleral buckle, filtering bleb or underwent any other ocular surgery within the past month

Design outcomes

Primary

Measure	Time frame	Description
Discomfort During Scleral Depression with Schocket Depressor and Cotton Tipped Applicator	Pain evaluated immediately scleral depression was completed on the eye	Visual Analog Scale (VAS) was used to evaluate pain immediately after scleral depression was completed. The VAS scale used was a 100mm long line with 0 representing no pain at all and 100 representing the worst pain possible.

Secondary

Measure	Time frame	Description
Hemoglobin A1c	1 year	The association of discomfort experienced during scleral depression and the patients hemoglobin A1c.
Spherical Equivalent of Glasses Prescription	1 day	The association of discomfort experienced during scleral depression and the patients spherical equivalent of their glasses prescription.
Age	1 day	The association of discomfort experienced during scleral depression and the patients age based on those less than 65 versus those greater than 65 years of age
Left Eye vs Right Eye	1 day	The association of discomfort experienced during scleral depression and the patients left and right eyes. Of note, each eye had a separate method of scleral depression performed.
Retinal pathology	1 day	Discomfort during scleral depression in participants with peripheral retinal tears or holes versus patients with no peripheral retinal pathology.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026