Cancer, Low Anterior Resection Syndrome, Quality of Life
Conditions
Brief summary
This study adds to the understanding of the contributing factors leading to LARS, the long term effects of this syndrome post-operatively and its impact on quality of life.
Interventions
PROCEDUREanterior resection
The distance from anal verge, preoperative radiotherapy and presence of stoma were analysed
Sponsors
University of Malta
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* All adult patients \>18 years, under the care of all surgical firms at Mater Dei Hospital, who had undergone anterior resection for rectal cancer between January 2014 and December 2016
Exclusion criteria
* colorectal cancer (\>15cm) from anal verge * permanent stoma * known disseminated or recurrent disease, * patient without restitution of bowel continuity after 1 year
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| LARS incidence | 1 year | Incidence of LARS in patients who had anterior resection |
| Risk factors | 1 year | Variable factors which might have contributed to LARS were the following: * Age * Gender * Diabetes mellitus * Pathological stage * MRI stage * Distance from anal verge * Surgical technique * Preoperative radiotherapy * Preoperative chemotherapy * Postoperative radio/chemotherapy * Type of anastomosis * Presence of stoma * Interval from stoma reversal * Duration of follow-up |
| Life | 1 year | The association between LARS and quality of life was assessed. |
Countries
Malta
Outcome results
None listed