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Exercise Intervention on Conflict Monitoring in Children With Attention-deficit Hyperactivity Disorder

The Effect of Long-term High-intensity Interval Training on Conflict Monitoring in Children With ADHD: an ERP and sLORETA Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04112758
Acronym
ADHD
Enrollment
110
Registered
2019-10-02
Start date
2020-06-01
Completion date
2022-01-23
Last updated
2023-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise Intervention

Keywords

HIIT, executive function, ADHD, chronic exercise

Brief summary

The study mainly investigates the effect of high-intensity interval training on conflict monitoring in children with ADHD by using event-related potential and sLORETA techniques.

Detailed description

The present study will have two experiments, one is a cross-section study and the other is intervention study. As for cross-section study, typical developmental children and children with ADHD will perform the stroop task while recording their brain waves. The intervention is twice a week for 5 weeks and before and after the intervention, children with ADHD will randomly assign to either an exercise group or control group. They will perform the stroop task while recording their brain waves.

Interventions

OTHERHigh-intensity interval training

2 times weekly for 5 weeks Circuit training with 4 stations

Sponsors

National Taiwan Normal University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
7 Years to 12 Years
Healthy volunteers
Yes

Inclusion criteria

1. age between 7 and 12 years 2. diagnosed with ADHD by a pediatric psychiatrist, which is not required for TD 3. no history of brain injury or neurological conditions, such as exhibited epileptic seizures, serious head injuries, and periods of unconsciousness.

Exclusion criteria

1. cannot follow the instruction 2. cannot complete all the procedure

Design outcomes

Primary

MeasureTime frameDescription
Behavioral performanceDay 0 and post-intervention at Week 5reaction time (ms) is generated by computerized task defined as correct responses within the range from 200-1500 ms

Secondary

MeasureTime frameDescription
N2 & P3 componentsDay 0 and post-intervention at Week 5Electroencephalographic (EEG) activity will be measured at 64 sites. The amplitude of the N2 is defined as the mean amplitude within a 50-ms interval surrounding the maximal negative peak within a 200- to 400-ms latency window. The amplitude of the P3 is defined as the mean amplitude within a 50-ms interval surrounding the maximal positive peak within a 300- to 800-ms latency window.

Other

MeasureTime frameDescription
Brain activationDay 0 and post-intervention at Week 5To examine sources relating to amplitude in ERPs, source localization will be conducted using standardized low resolution brain electromagnetic tomography (sLORETA) The sLORETA analysis with the ERP data will be selected by four 100 ms bins covering the period from 0 to 200 ms after stimulus-onset (0-50, 50-100, 100-150, and 150-200 ms).

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026