Effect Of Delta Sodium on the Postoperative Outcomes in Liver Transplant Recipients

Effect of Perioperative Delta Sodium on Outcomes in Liver Transplant Recipients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04112004

Acronym

SOLT

Enrollment

342

Registered

2019-10-02

Start date

2011-01-01

Completion date

2017-12-31

Last updated

2019-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Electrolyte Disturbance, Liver Transplant; Complications, Perioperative/Postoperative Complications

Keywords

liver transplantation, perioperative sodium, sodium

Brief summary

We analyzed the association of delta sodium levels with their effect on post liver transplant outcomes in consecutive patients undergoing liver transplantation. Records were analyzed for electrolytes and outcome measures, and data was analyzed.

Detailed description

Preoperative hyponatremia was identified in patients. The mean change in sodium in hyponatremic patients was compared with inpatients with normal sodium levels. The impact of the delta sodium levels with short-term outcomes, such as duration of intubation, intensive care unit length of stay were analyzed with univariate and multivariate logistic regression analyses.

Interventions

OTHERCollecting sodium reports and outcome measures

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* All liver transplant recipients between Jan 2011 to Jan 2017 * Records available

Exclusion criteria

* Acute fulminant liver failure * All patients less than 18 years * Re operated cases * Pregnant patients

Design outcomes

Primary

Measure	Time frame	Description
change in serum sodium in liver transplant recipients	1 day	difference between baseline and postoperative sodium in liver transplant recipients
post transplant mortality	1 month	post transplant mortality after liver transplantation

Secondary

Measure	Time frame	Description
post operative neurological complications	1 month	Post operative neurological complications after liver transplantation
duration of mechanical ventilation	1 month	duration of mechanical ventilation after liver transplantation
Duration of hospital stay	1 month	Hospital stay after liver transplantation
Duration of ICU stay	1 month	Duration of ICU stay after liver transplantation

Countries

India

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026