Parkinson Disease, Quality of Life
Conditions
Brief summary
This study aim to evaluate the correlation between Quality of Life (QoL) and severity of Parkinson's Disease (PD) by assessing the presence of an optimal cut-off point on the Parkinson's disease questionnaire (PDQ-39) as related to the Hoehn & Yahr (H&Y) scale in a cohort of Italian adults with PD. A multicenter, cross-sectional study was performed in central and northern Italy. This study was conducted on a cohort of consecutive individuals at three neurologic outpatient clinics. All participants were evaluated with the PDQ-39, and the severity of PD was recorded according to the H&Y scale by a neurologist. Receiver operating characteristic (ROC) curves and coordinates of the curve, which were visually inspected, were used to find cut-off points with optimal sensitivity and specificity. These were in turn used to determine the optimal PDQ-39 cut-off score for identifying disease severity according to H&Y stages.
Interventions
OTHERno intervention
All participants were evaluated with the PDQ-39, and the severity of PD was recorded according to the H&Y scale by a neurologist.
Sponsors
R.O.M.A. - Rehabilitation & Outcome Measures Assessment
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
50 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* age \> 50 but \< 90 years, * H&Y stages I, II, III, and IV, * a mini-mental state examination \> 22 points, * a minimum level of five years of education.
Exclusion criteria
* Individuals with emotional or psychiatric problems (as determined by clinical screening)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hoehn & Yahr (H&Y) | at admission to the neurologic outpatient clinics | severity of Parkinson's disease |
| Parkinson's Disease questionnaire (PDQ-39) | at admission to the neurologic outpatient clinics | quality of life |
Countries
Italy
Outcome results
None listed