Hemodynamic Monitoring, Laparoscopic Surgery, Oxytocin
Conditions
Keywords
Oxytocin, Hemodynamic, Myomectomy
Brief summary
This project will study the effect of oxytocin on hemodynamics in patients undergoing laparoscopic myomectomy, and how to prevent and manage such hemodynamic changes effectively.It provides a reference for the rational use of oxytocin in clinical practice, which can not only effectively contract the uterus and reduce bleeding, but also reduce the influence on hemodynamics.
Interventions
DRUGOxytocin
During the laparoscopic hysteromyomectomia operation, different doses of oxytocin was used with different routs.
Sponsors
Yangzhou University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* General anesthesia for gynecological laparoscopic surgery,ASA I\ III
Exclusion criteria
* Oxytocin use contraindications
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes of traditional hemodynamic parameters after oxytocin use during laparoscopic hysteromyomectomia. | before induction, before incision, before oxytocin intramuscular injection, and 20 sec, 40 sec, 60 sec, 80 sec, 100 sec, 120 sec, 140 sec, 160 sec,180 sec after oxytocin intramuscular injection. | Parameters including SBP, DBP, MAP (mmHg) were measured by a Mostcare hemodynamic monitor. |
| Changes of volume management parameters after oxytocin use during laparoscopic hysteromyomectomia. | before induction, before incision, before oxytocin intramuscular injection, and 20 sec, 40 sec, 60 sec, 80 sec, 100 sec, 120 sec, 140 sec, 160 sec,180 sec after oxytocin intramuscular injection. | SVV (%) was measured by a Mostcare hemodynamic monitor. |
Countries
China
Contacts
Primary ContactZhuan Zhang
Outcome results
None listed