Labor, Premature
Conditions
Brief summary
During pregnancy , the maternal immune system is always confronted with fetal alloantigens. the immunological mechanisms that prevent the rejection of the fetus are still not under understood.
Detailed description
During pregnancy , the maternal immune system is always confronted with fetal alloantigens. the immunological mechanisms that prevent the rejection of the fetus are still not under understood.the fetus is normally accepted by the maternal immune system despite despite the expression of paternal alloantigens. Normally, the fetus grows and develops very well with ongoing pregnancy. B regulatory cells are increased in pregnant women compared to non-pregnant women.
Interventions
DIETARY_SUPPLEMENTInvestigation
Cross sectional intervention
Sponsors
Assiut University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy female according to the required groups
Exclusion criteria
* patient with infectious disease , tuberculosis ,tumor ,hematologic disease,metabolic bone disease or any other connective tissue diseases were excluded. * Patient with viral hepatitis. * serological evidence of HIV infection.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in number of B regulatory cell in pregnant woman | 9 months | Immune system immunosuppressed to maintain fetus |
Countries
Egypt
Contacts
Primary ContactKhalid Hassanein, Professor
Backup ContactHelal Hetta, Lecturer
Outcome results
None listed