Acute Coronary Syndrome
Conditions
Keywords
Cardiac rehabilitation, Physical activity, Force-velocity profile, Autonomic nervous system, Coronary artery disease
Brief summary
Cardiac rehabilitation includes aerobic and anaerobic training adapted to cardiovascular pathology for which cardiac rehabilitation is prescribed. It is essential to adapt the content of these cardiac rehabilitation sessions to optimize aerobic and anaerobic performance and quality of life. Improvement of the first ventilatory threshold is one of the main objectives since it illustrates the adaptation of the patient to submaximal exercise, typical of everyday life. The research laboratory Autonomous Nervous System - Epidemiology, Physiology, Engineering, Health (SPA-EPIS) has an international expertise in training optimization in top-athletes. He have shown the importance of the relationship between the power-force-velocity profile and athletes performances.
Detailed description
In this sudy, each patient has a force and a velocity that can be optimized with training to achieve maximum power. This optimization can be evaluated through a force-velocity profile, measured from an only sprint on a cycloergometer. The hypothesis that force-velocity profile could be used in cardiac rehabilitation in coronary patients to induce a force-velocity balance adapted through personalized sessions and regular medical follow-up. This prospective, controlled, randomized and open label study will attempt to evaluate further the relevance of force or velocity training based on the initial force-velocity profile of coronary patients included in the cardiac rehabilitation program in the University Hospital of Saint-Etienne.
Interventions
OTHERSprints
Two sprints of 8 seconds on a cycle ergometer will be performed for determine Force/Velocity Profile (FVP). Realized at inclusion and 2 months after.
OTHERVertical jumps
Two vertical jumps will be performed. Height of theses vertical jumps will be measured by application My jump 2 to determine muscle power. Realized at inclusion and 2 months after.
OTHERQuestionary Short Form-12 (SF-12)
Questionary Short Form-12 (SF-12) will be performed to evaluate quality of life. It is composed of 12 questions. Realized at inclusion and 2 months after.
DEVICEactivity actigraph
Activity actigraph will be wearing by patient during 7 consecutive days. It measures the level of physical activity and the sedentary lifestyle of patients. Realized at inclusion and 2 months after.
OTHERProgram composed of two 2 training strategies
Program composed of two 2 training strategies according to the initial Force/Velocity Profile (FVP) will be realized at the inclusion. There are : * Strategy experimental-speed: speed training strategy for subjects with a force-speed profile (PFV) in favour of force * Strategy experimental-force: force training strategy for subjects with a force-speed profile (PFV) in favour of speed.
OTHERProgram of usual practice
Program composed of training in force and speed independently of the initial Force/Velocity Profile (FVP).
Sponsors
Jean Monnet University
Centre Hospitalier Universitaire de Saint Etienne
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Acute coronary syndrome treated within the last 6 months * Medical revascularization (angioplasty ± stenting) or surgical (coronary artery bypass) * During initial effort test: Maximum aerobic power≥ 60 watts for women and ≥ 80 watts for men * Patient affiliated or beneficiary to social security * Signed informed consent
Exclusion criteria
* Significant co-morbidities limited practice of physical activity * Inability to submit to medical monitoring of the program * Patient deprived of liberty or patient under guardianship * Pregnant woman
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| volume of oxygen consumed (VO2) (in ml/min/kg) at the first ventilatory threshold (SV1) | Months: 0 and 2 | Change in VO2 (volume of oxygen in ml/min/kg) at the first ventilatory threshold (SV1) during a Cardio-Pulmonary Exercise Test (CPET). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Power at first ventilatory threshold (SV1) | Months: 0 and 2 | Comparison value of power at first ventilatory threshold (SV1) during a Cardio-Pulmonary Exercise Test (CPET). |
| Maximum aerobic power (in watt) | Months: 0 and 2 | Comparison maximum aerobic power (in watt) during a Cardio-Pulmonary Exercise Test (CPET). |
| Voluntary muscle power (in kg) during a static muscle testing on quadriceps | Months: 0 and 2 | Comparison voluntary muscle power (in kg) during a static muscle testing on quadriceps. |
| Voluntary muscle power (in kg) during a dynamic muscle testing on quadriceps | Months: 0 and 2 | Comparison voluntary muscle power (in kg) during a dynamic muscle testing on quadriceps. |
| Value of muscular endurance (in min) during a static muscle testing on quadriceps | Months: 0 and 2 | Comparison value of muscular endurance (in min) during a static muscle testing on quadriceps. |
| VO2 max (volume of oxygen maximum in ml/min/kg) | Months: 0 and 2 | Comparison VO2 max (volume of oxygen maximum in ml/min/kg) during a Cardio-Pulmonary Exercise Test (CPET). |
| Standard Deviation of the Normal R-R interval (SDNN) index | Months: 0 and 2 | Measured by holter electrocardiogram during 24 hours. |
| BaroReflex Sensitivity (BRS) (in ms/mmHg) | Months: 0 and 2 | Measured by baroreflex. |
| Physical activity (in Metabolic Equivalent of Task (MET)-min/week) | Month: 0 | Assessment of Physical activity (in Metabolic Equivalent of Task (MET)-min/week). Measured by activity actigraph. |
| Sedentary life (in hour/day) | Month: 0 | Assessment of Sedentary life (in hour/day). Measured by activity actigraph. |
| SF-12 questionnaire score | Months: 0 and 2 | The SF-12 is a self-questionnaire to assess the quality of life. This tool is an abbreviated version of the Medical Outcomes Study Short-Form General Health Survey (SF-36) contains only 12 items out of 36 with minimum score 0 (bad quality life) and maximum score at 100 (good quality life). |
| Value of muscular endurance (in min) during a dynamic muscle testing on quadriceps | Months: 0 and 2 | Comparison value of muscular endurance (in min) during a dynamic muscle testing on quadriceps. |
Countries
France
Outcome results
None listed