CKD Stage 4
Conditions
Brief summary
The current study is planned to assess possible relationships of serum hepcidin levels with haemoglobin levels, inflammation and iron statuses in stage 4 CKD patients.
Interventions
DIAGNOSTIC_TESTserum hepcidin
it is a serum marker
Sponsors
Assiut University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Adult patients (\>18 years) with anaemia who had CKD stage 4 with glomerular filtration rate (GFR) 15-29 ml/min/1.73 m2
Exclusion criteria
* Subjects with blood transfusion within the preceding 3 months. myocardial infarction (MI) history within the preceding 3 months, surgical history within the preceding 3 months, malignancy. Advanced liver cirrhosis. uncontrolled diabetes
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| relation between serum hepcidin level and ESR ckd stage 4 | at study entry and then again after 3 months | measure strength of relation, r, between levels of serum hepcidin and ESR, an inflammation marker |
| relation between serum hepcidin and serum ferritin levels | at study entry and then again after 3 months | measure strength of relation, r, between levels of hecidin and ferritin |
Contacts
Primary ContactDeiaaeldeen Mohamed, master degree
Outcome results
None listed