Cataract, Dry Eye
Conditions
Brief summary
To study the efficacy of an ocular bandage contact lens for the treatment of dry eye after cataract surgery
Interventions
DEVICEbandage contact lenses
wear bandage contact lensesfor a week after cataract surgery.
PROCEDUREphacoemulsification
underwent standard phacoemulsification through a 2.8-mm clear corneal temporal incision and intraocular lens
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. age-related cataract 2. dry eye disease
Exclusion criteria
1. a history of surgery and other ocular diseases 2. contact lens use 3. ocular therapies such as 0.05% cyclosporine A or steroids in the last 3 months. had 4.any systemic diseases such as heart diseases, diabetes and psychosis.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| slit-lamp examination | 0 day | slit-lamp examination |
| Change from Baseline Ocular Surface Disease Index at 1 week | 0 day, 1 week postoperative | Ocular Surface Disease Index |
| Change from Baseline Ocular Surface Disease Index at 1 month | 0 day, 1 month postoperative | Ocular Surface Disease Index |
| Change from Baseline meibography score at 1 week | 0 day, 1 week postoperative | meibography score |
| Change from Baseline meibography score at 1 month | 0 day, 1 month postoperative | meibography score |
| Change from Baseline of non-invasive keratograph tear meniscus height at 1 month | 0 day, 1 month postoperative | non-invasive keratograph tear meniscus height |
| Change from Baseline of non-invasive keratograph tear meniscus height at 1 week | 0 day, 1 week postoperative | non-invasive keratograph tear meniscus height |
| Change from Baseline noninvasive tear breakup time at 1 week | 0 day, 1 week postoperative | noninvasive tear breakup time |
| Change from Baseline noninvasive tear breakup time at 1 month | 0 day, 1 month postoperative | noninvasive tear breakup time |
| Change from Baseline Schirmer I test at 1 week | 0 day, 1 week postoperative | Schirmer I test |
| Change from Baseline Schirmer I test at 1 month | 0 day, 1 month postoperative | Schirmer I test |
| Change from Baseline IL-1, IL-6, IL-12, IL-10, IL-8, TNF-α and ICAM-1 level at 1 month | 0 day and 1 month postoperative | cytokine levels |
Countries
China
Outcome results
None listed