Anesthesia, Rigid Bronchoscopy, Safety, Tracheal Intubation, Transbronchial Cryobiopsy
Conditions
Keywords
Transbronchial Cryobiopsy, anesthesia, tracheal intubation, rigid bronchoscopy, safety, interstitial lung disease
Brief summary
to evaluate the difference between the tracheal intubation (TI) and rigid bronchoscopy (RB) under general anesthesia on patients with transbronchial cryobiopsy.
Detailed description
To evaluate the difference between the tracheal intubation (TI) and rigid bronchoscopy (RB) under general anesthesia on patients with transbronchial cryobiopsy. Comparing the difference between two groups in the operating duration, extubation duration, total anesthesia time, heart rate, blood pressure and arterial blood gas analysis. This is a prospective, randomized, controlled trial.
Interventions
PROCEDUREanesthesia
patient was insert trachial intubation or rigid bronchoscopy with ventilation under general anesthesia
Sponsors
Guangzhou Institute of Respiratory Disease
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
1. The patients are admitted in the institution as ILD, while undefined after thorough history collection, laboratory examination and radiological data. 2. Transbronchial cryobiopsy(TBCB) is indicated by clinicians for definitive diagnosis and patients are content with the examination with agreement signed. 3. Blood gas analysis, routine blood test, ECG examination, coagulation function, immunological examination, chest HRCT, and liver/kidney function test have been completed
Exclusion criteria
1. The radiological data indicates non-ILD 2. The clinical examinations mentioned above are not completed. 3. The patient cannot endure or does not agree the procedure.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the fluctuation of heart rate | 24 hours | fluctuation of heart rate during the procedure |
| the fluctuation of blood pressure | 24 hours | the fluctuation of blood pressure during the procedure |
| the fluctuation of arterial partial pressure of carbon dioxide | 24 hours | the fluctuation of arterial partial pressure of carbon dioxide during the procedure |
Countries
China
Contacts
Primary ContactShiyue Li, master
Backup ContactXiaobo Chen, master
Outcome results
None listed