Transversus Thoracic Muscle Plane Block for Open Heart Surgery

Ultrasound Guided Transversus Thoracic Muscle Plane Block for Open Heart Surgery: Randomized Controlled Double Blind Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04094532

Acronym

TTMP

Enrollment

Registered

2019-09-19

Start date

2019-10-01

Completion date

2020-01-15

Last updated

2020-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Acute, Pain, Chest

Brief summary

Poststernotomy pain is a complication of cardiac surgery. Poorly controlled pain is associated with myocardial ischemia, cardiac arrhythmias, hypercoagulability, pulmonary complications, and increased rates of delirium and wound infection. The transverse thoracic muscle plane (TTMP) block is a novel plane block that provide pain for sternotomy. The aim of this study was to evaluate the analgesic effect of ultrasound guided TTMP block in patients undergoing open heart surgery.

Interventions

DRUGBupivacaine

Ultrasound guided 20 ml % 0.250 bupivacaine injection to transverse thoracic muscle plane bilaterally

DRUGSaline

Ultrasound guided 20 ml % 0.9 saline injection to transverse thoracic muscle plane bilaterally

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

American Society of Anesthesiologist's physiologic state I-III patients Undergoing Open Heart Surgery

Exclusion criteria

chronic pain bleeding disorders renal or hepatic insufficiency patients on chronic non-steroidal anti-inflammatory medications emergency cases

Design outcomes

Primary

Measure	Time frame	Description
Postoperative opioid consumption	first 24 hours	First 24 hours total fentanyl consumption with patient controlled analgesia

Secondary

Measure	Time frame	Description
Visual analog pain score	postextubation 0-24 hours	Post operative pain will be evaluated with a Visual Analogue Scale (VAS) score of 0-10 (0= no pain and 10= worst imaginable pain)

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026