Polycystic Ovary Syndrome
Conditions
Brief summary
Stein and Leventhal were the first to recognize an association between the presence of polycystic ovaries and signs of hirsutism and amenorrhea (eg,oligomenorrhea, obesity), After women diagnosed with Stein-Leventhal syndrome underwent successful wedge resection of the ovaries, their menstrual cycles became regular, and they were able to conceive. As a consequence, a primary ovarian defect was thought to be the main culprit, and the disorder came to be known as polycystic ovarian disease.
Interventions
DRUGCetrorelix
0.25 mg subcutaneous injection daily for 6 days
DRUGLeuprolide Acetate
0.1 mg subcutaneous injection daily for 12 days
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
1. Women under 35 years with polycystic ovary syndrome criteria 2. Normal male semen parameters 3. Normal tubes either by hysterosalpingography &/or laparoscopy 4. Free from other endocrine abnormalities
Exclusion criteria
1. NON polycystic ovary syndrome Criteria 2. More than 35 years 3. Abnormal semen parameters 4. Pathological tube& pelvic factor 5. Other endocrine disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The difference in clinical pregnancy rate in both groups | 6 weeks | ultrasound detection of fetal heart pulsations |
Countries
Egypt
Contacts
Primary ContactMohammed Smeeh, MSc
Outcome results
None listed