Perioperative Risk Calculator

Machine-learning Model for Perioperative Risk Calculation

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04092933

Acronym

PROTECT

Enrollment

175559

Registered

2019-09-17

Start date

2014-05-01

Completion date

2024-12-31

Last updated

2023-11-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative/Postoperative Complications

Keywords

machine learning, decision support, risk calculator, anesthesia

Brief summary

The aim of this project is to develop a machine-learning model for calculating the risk of postoperative complications. In addition to the data collected during the premedication, the model will include all intraoperative values recorded in the Patient Data Management System (PDMS), which include not only vital and respiratory parameters, but also medication and doses, intraoperative events and times. Postoperative complications are defined according to their severity according to the Clavien-Dindo score (Dindo, Demartines et al., 2004) and are collected from the data available in the health information system (HIS). The machine-learning model is created using an extreme-gradient boosting algorithm which has been updated with new data from the year 2021 to ensure accuracy of the model.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* all patients who underwent surgery with anesthesia

Exclusion criteria

* none

Design outcomes

Primary

Measure	Time frame	Description
postoperative complications	30 days	Postoperative complications are classified by means of the Clavien-Dindo-Score. The Clavien-Dindo-Score describes classes of severity of postoperative complications: Grade I: any deviation from the normal postoperative course without the need for pharmacological treatment or surgical, endoscopic and radiological interventions Grade II: requiring pharmacological treatment Grade IIIa: requiring surgical, endoscopic or radiological intervention not under general anesthesia Grade IIIb: requiring surgical, endoscopic or radiological intervention under general anesthesia Grade IVa: single organ dysfunction Grade IVb: multiorgandysfunction Grade V: death of a patient

Secondary

Measure	Time frame	Description
in-hospital mortality	30 days	mortality within hospital stay

Outcome results