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Optic Nerve Sheath Diameter in Prediction of Fluid Responsiveness

Prospective Study: Optic Nerve Sheath Diameter in Prediction of Fluid Responsiveness

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04092036
Enrollment
45
Registered
2019-09-17
Start date
2019-10-15
Completion date
2020-03-14
Last updated
2019-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fluid Responsiveness, Optic Nerve Sheath Diameter, Shock

Brief summary

The aim of the study to examine Optic Nerve Sheath Diameter measurement for prediction of fluid responsiveness in hemodynamically unstable patients

Interventions

DEVICEOptic Nerve Sheath Diameter (ONSD) measurement by ultrasound

ONSD measurements will be performed in the supine patient. Ultrasound gel will be applied over the closed upper eyelid. The ultrasound probe will be placed on the temporal area of the eyelid. Then the probe will be angled in order to display the entry of the optic nerve into the globe. ONSD will be measured 3 mm behind the globe in the transverse plane perpendicular to the optic nerve. For each optic nerve three measurements will be made. The ONSD corresponds to the mean of the six values which will be obtained from each patient (three measurements for each eye).

Sponsors

Tanta University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Patients on mechanical ventilation * 18 years or older * patients developing hypotension (Mean arterial blood pressure) \<65 mmHg

Exclusion criteria

* Patients with Spontaneously breathing activity. * Patients with a history of intracranial disease e.g. (stroke, TBI, causes of increased intracranial pressure). * local cause in the eye as (Glaucoma, Single eye) * Need for high PEEP. * Known history of cardiac disease. * Organ/s failure at admission

Design outcomes

Primary

MeasureTime frame
The cut-off value of optic nerve sheath diameter (ONSD) for prediction of fluid responsivenessfirst day

Secondary

MeasureTime frame
Correlation between Stroke Volume Variation (by electrical cardiometry) and ONSDfirst day

Contacts

Primary ContactHadeel Ibraheim Elsagheir, MBBCH
HadeelElsagheir@gmail.com00201090884208

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026