Safety and Effectiveness of Ticagrelor in Patients Undergoing Carotid Stenting

Status

UNKNOWN

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04091074

Enrollment

Registered

2019-09-16

Start date

2022-01-01

Completion date

2022-12-01

Last updated

2021-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carotid Stenosis

Brief summary

patients undergoing carotid stenting take dual anti platelet therapy to prevent thrombotic complications usually used drugs are aspirin plus clopidogrel but there are patients not respond so ticagrelor may be an effective and safe alternative

Interventions

DRUGTicagrelor

Half of patients undergoing carotid stenting take ticagrelor+aspirin

DRUGClopidogrel

Other half ofpatients undergoing carotid stenting take clopidogrel+aspirin

PROCEDURECarotid stenting

Patients with carotid stenosis will undergo carotid stenting

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

1. Ischemis stroke of both sex. 2. More than 18 years. 3. Accepting all study requirements.

Exclusion criteria

1. Refuse to comply with all study requirements. 2. bleeding tendency or liver diseases

Design outcomes

Primary

Measure	Time frame	Description
compare efficacy of ticagrelor and clopidogrel in patients undergoing carotid stenting	15 days before carotid stenting	patients undergoing carotid stenting are divided into 2 groups comparing efficacy of ticagrelor and clopidogrel
Compare safety of ticagrelor and clopidogrel in patients undergoing carotid stenting	15 days before carotid stenting	Patients undergoing carotid stenting are divided into two groups comparing safety of ticagrelor and clopidogrel

Secondary

Measure	Time frame	Description
Pattern of carotid stenosis	1 year	Incidence of carotid stenosis in patients come to Assiut university hospitals

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026