Chronic Tic Disorder, Tourette Syndrome in Adolescence, Tourette Syndrome in Children
Conditions
Keywords
tics, tourette Syndrome
Brief summary
To evaluate the effect and acceptability of an Internet-based comprehensive behavioral intervention for tics (ICBIT) in a sample of children and adolescents with Tic disorders. children and adolescents (aged 8-17 years) with Tourette Syndrome (TS) or Chronic Tic Disorder (CTD) and their parents will be randomly assigned to receive either an Internet-based ICBIT or wait-list (WL).
Detailed description
To evaluate the effect and acceptability of an Internet-based comprehensive behavioral intervention for tics (ICBIT) in a sample of children and adolescents with Tic disorders, children and adolescents (aged 8-17 years) with Tourette Syndrome (TS) or Chronic Tic Disorder (CTD) and their parents will be randomly assigned to receive either an Internet-based ICBIT or wait-list (WL) condition in a cross over design. Participants will be randomized to ICBIT, or to wait list, and half will cross over from wait list to ICBT. Two blind independent clinical evaluators will rate tic severity and comorbidity. The primary outcome measure is the Yale Global Tic Severity Scale (YGTSS). Assessments will be performed at baseline, post-ICBT or post wait list, 3-months and 6-months (post-treatment for those originally assigned to ICBT) and post-ICBT, 3-months and 6-months (post-treatment for those originally assigned to wait list condition). All assessments were conducted by 2 PhD level independent child psychologists.
Interventions
BEHAVIORALICBIT
The intervention consists of 9 modules delivered over 9 weeks comprise of age-appropriate texts and descriptive diagrams, animations, films of clinicians demonstrating techniques such as competing response exercising.
BEHAVIORALwaiting list
Participants initially assigned to the wait list received no psychosocial intervention for 9 weeks. Following post-WL assessment, all participants chose to receive ICBIT.
Sponsors
Tel Aviv Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
8 Years to 17 Years
Healthy volunteers
Yes
Inclusion criteria
* Clinical diagnosis of Tourette Syndrome or Chronic Tic Disorder. * Yale Global Tic Severity Scale tic severity score ≥14.
Exclusion criteria
* Change in psychotropic medication regimen during the past 6 weeks. * Current diagnosis of substance abuse/dependence. * Lifetime diagnosis of pervasive developmental disorder, mania or psychosis. * Previous sessions of CBIT.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Yale Global Tic Severity Scale (YGTSS) | change from baseline YGTSS total score at 3 months |
Countries
Israel
Contacts
Primary ContactLilch Rachamim
Backup ContactMichael Rotstein, MD
Outcome results
None listed