Skip to content

Prevalence and Burden of Bronchiectasis in Tuberculous Patients

Prevalence and Burden of Bronchiectasis in Tuberculous Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04085133
Enrollment
50
Registered
2019-09-11
Start date
2019-09-26
Completion date
2020-04-01
Last updated
2023-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Tuberculoses

Brief summary

Bronchiectasis was described in the early 19th century by Laennec. Bronchiectasis is a chronic condition characterized by permanent and irreversible dilatation of the bronchial airways and impairment of mucociliary transport mechanism due to repeated infection and inflammation leading to colonization of organism and pooling of the mucus in the bronchial tree

Detailed description

Bronchiectasis was described in the early 19th century by Laennec. Bronchiectasis is a chronic condition characterized by permanent and irreversible dilatation of the bronchial airways and impairment of mucociliary transport mechanism due to repeated infection and inflammation leading to colonization of organism and pooling of the mucus in the bronchial tree. The prevalence of bronchiectasis is age-related and occurs in every age group and in the pre-antibiotic era . it most often began in childhood. Recent evidence shows that bronchiectasis disproportionately affects women and older individuals and will be contributing to increase in healthcare burden.\[3\] International data show an increase in the prevalence of bronchiectasis over recent years.

Interventions

DIAGNOSTIC_TESTGene Xpert Chest x ray and MSCT chest

Sputum sample for T.B will be done using gene expert device and chest xray and high resolution ct to evaluate bronchectasis

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 50 Years

Inclusion criteria

* 1-patients were diagnosed to have tuberculosis by sputum culture and gene x pert. 2-patients were diagnosed to have bronchiectasis after lab and radiological examination as well as clinical score. 3- patients diagnosed as bronchiectasis after history of tuberculosis or anti Tuberculosis treatment with positive or negative tuberculous culture in the time of research.

Exclusion criteria

* 1-patients presented with other Pulmonary diseases. 2-Chronic liver and renal disease . 3- Lung cancer and tumors. 4- patients were previously diagnosed as bronchiectasis .

Design outcomes

Primary

MeasureTime frameDescription
To study prevalence of bronchiectasis in TB patients by case per year.One yearHow many patients of TB will be diagnosed as abronchiectasis

Secondary

MeasureTime frameDescription
To evaluate the burden of bronchiectasis in TB patientsone yearby frequency of need for hospital admission per year, need for outpatient clinical visits per month and frequency of need for antimicrobial therapy other than anti-tuberculous treatment per month

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026