Mycoprotein and Muscle Protein Synthetic Response

Comparing the Muscle Protein Synthetic Response to Ingestion of Mycoprotein vs Protein Isolated From Mycoprotein

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04084652

Acronym

PIMP

Enrollment

Registered

2019-09-10

Start date

2019-04-15

Completion date

2019-12-11

Last updated

2022-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anabolic Response to Mycoprotein and Micronutrient Ingeston

Brief summary

Dietary protein is vital for the preservation of health and optimal adaptation to training. However, traditional animal proteins come with a number of economic, environmental, and ethical issues. Accordingly, there is a need to develop an understanding of the utility of more sustainable non-animal derived dietary proteins to support our nutrition. Mycoprotein, produced by Quorn Foods™, has recently been shown to stimulate a greater anabolic response within skeletal muscle compared with milk protein, suggesting its utility within sports nutrition. However, it is unclear what accounted for the greater anabolic response of mycoprotein. One explanation could be the non-protein nutrients contained within mycoprotein (e.g. fibre, carbohydrate, fat or micronutrients). Therefore, the present study will compare the muscle anabolic response between mycoprotein (MYC) as a whole food and the protein isolated from mycoprotein (PIM).

Interventions

DIETARY_SUPPLEMENTMycoprotein ingestion

The ingestion of mycoprotein

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

MALE

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* BMI between 18 and 30. * Resistance trained

Exclusion criteria

* Any metabolic impairments. * Cardio/pulmonary diseases. * Chronic use of over the counter pharmaceuticals * A personal or family history of epilepsy, seizures or schizophrenia. * Allergic to mycoprotein/Quorn/edible fungi/environmental mould products.

Design outcomes

Primary

Measure	Time frame	Description
Muscle protein synthesis	7.5 hours	The rate of synthesis of new muscle protein (Fractional Synthetic Rate %/h)

Secondary

Measure	Time frame	Description
Plasma Amino Acid Kinetics	7.5 hours	The rate of appearance of amino acids ingested in the drink
Blood Glucose	7.5 hours	The levels of glucose in the blood
Serum Insulin	7.5 hours	The levels of insulin in blood serum

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026