Appendicitis Acute, Laparoscopic Surgery
Conditions
Keywords
Laparoscopic appendectomy, Endoloop, Endostapler, Endoclip
Brief summary
In this randomized control trial the patients with acute appendicitis will be divided in three groups according to the management of the appendiceal stump(Endostapler, Endoloop or Endoclip). Pre-, peri- and postoperative data will be analysed.
Detailed description
Acute appendicitis is the most common indication for intraabdominal emergency surgery, and appendectomy is one of the most commonly performed procedures in abdominal surgery. Today laparoscopic appendectomy (LA) has the status of a ''Gold Standard'' treatment, and it is accepted as the treatment of choice for acute appendicitis.There are several ways of closing the appendiceal stump.An inadequate closure of the appendiceal stump can lead to morbidity of operated patients. The aim of this study is to assess the efficiency of different closure techniques by focusing on the intraoperative and postoperative complications.The patients will be divided into three groups based on the technique used for appendiceal stump closure, whether it is Endoloop, Endostapler or Endoclip. In the patients included in the study the investigators will analyse demographic data, peroperative laboratory values, clinical data and treatment outcomes. Also, the histopathological findings of the specimens and perioperative and postoperative complications will be analysed.
Interventions
DEVICETechnique used for closing the appendiceal stump
In all patients, laparoscopic appendectomy is performed, only difference is the way of managing appendiceal stump
Sponsors
University Hospital Dubrava
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients with clinically and radiologically(Ultrasound) verified appendicitis
Exclusion criteria
* Patients converted from laparoscopy to open surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Operative and postoperative complications | Seven postoperative days | Number of all complications will be presented in total numbers. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Histopathological findings | Seven days | Histopathological findings will be graduated in 3 grades - phlegmonous,gangrenous and perforated. |
| Percentage of reoperated patients | Seven days | Presented in percentages |
| Number of reoperated patients | Seven days | Presented in total numbers |
| Value levels of leukocytes | Before surgery | Whit blood cells count |
| Duration of symptoms | Before surgery | Duration of symptoms will be measured in hours. |
| Height | Before surgery | Meters |
| Weight | Before surgery | Kilograms |
| Hospital stay | Seven days | Length of the hospital stay will be presented in days. |
| Neutrophiles | Before surgery | Neutrophile count |
| Body mass index | Before surgery | Kilograms/meter square |
| Body temperature | Before surgery | Body temperature will be measured in degrees celsius. |
| Length of the operations | During operation | Length of the operations will be presented in minutes. |
| Closure of the appendiceal stump using Endoloop | During operation | Number of patients in which this technique was performed. |
| Closure of the appendiceal stump using Endostapler | During operation | Number of patients in which this technique was performed |
| Closure of the appendiceal stump using Endoclip | During operation | Number of patients in which this technique was performed |
| C-reactive protein | Before surgery | Milligrams/liter |
Countries
Croatia
Outcome results
None listed