Acute Kidney Injury in Adult Patients Supported by VA-ECMO

Risk Factors and Prognosis of Acute Kidney Injury in Peri Operative Cardiac Surgery Adult Patients Supported by VA-ECMO

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04082312

Acronym

AKI-ECMO

Enrollment

347

Registered

2019-09-09

Start date

2016-05-01

Completion date

2019-07-05

Last updated

2023-09-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury, Cardiogenic Shock

Keywords

Acute Kidney Injury, ECMO, Post Cardiogenic Shock Syndrome

Brief summary

Post-cardiotomy cardiogenic shock (PCCS) occurs in 2-6% of patients undergoing cardiac surgery, and 1% of cardiac surgery patients will require mechanical circulatory support using Veno-Arterial ExtraCorporeal Membrane Oxygenation (VA-ECMO). Acute Kidney Injury is a frequent complication in this population and negatively impacts the survival. We aimed to determine whether the timing of ECMO implantation influence the renal prognosis of these patients.

Interventions

OTHERNo intervention

No intervention

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 99 Years

Inclusion criteria

* All patients admitted in post-operative of cardiac surgery * Assisted by VA-ECMO

Exclusion criteria

* Chronic hemodialysis * Death occurring within the first 48 hours of VA-ECMO implantation * Multiple VA-ECMO during the same hospitalization.

Design outcomes

Primary

Measure	Time frame	Description
Occurrence of a stage 3 AKI	Day 10 after ECMO implantation	Number of Participants with Stage 3 Acute Kidney Injury according to the Kidney Disease: Improving Global Outcomes (KDIGO) group

Secondary

Measure	Time frame	Description
Mortality at Day 30	Day 30 after ECMO implantation	Number of Deceased Participants
Mortality at 6 months	6 months after ECMO implantation	Number of Deceased Participants

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026