Skip to content

Abdominal Aortic Aneurysm Patients Remain at Risk for Delirium on the Surgical Ward After Intensive Care Unit Dismissal

Abdominal Aortic Aneurysm Patients Remain at Risk for Delirium on the Surgical Ward After Intensive Care Unit Dismissal

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04080557
Enrollment
135
Registered
2019-09-06
Start date
2018-11-01
Completion date
2019-02-28
Last updated
2019-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AAA, Aortic Aneurysm, Abdominal, Delirium, Intensive Care Unit Delirium, Surgery, Surgery--Complications

Keywords

delirium, intensive care unit, surgical ward, abdominal aortic aneurysm surgery

Brief summary

The incidence of delirium following open abdominal aortic aneurysm (AAA) surgery is significant, with incidence rates ranging from 12 to 33%. The occurrence of delirium on the surgical ward after intensive care unit (ICU) dismissal in AAA patients remains unclear. Differences in outcomes between a delirium on the ICU and a delirium on the surgical ward have not been previously investigated. Delirium is a frequent complication in patients who underwent open AAA surgery. This study demonstrated that patients on the surgical ward remain at risk for developing a delirium after ICU dismissal. Physicians should therefore maintain a high level of awareness for delirium in AAA patients who return to the surgical ward after ICU dismissal. This simultaneously emphasises the necessity of delirium preventive measures and early recognition on the surgical ward in order to improve clinical outcomes.

Detailed description

The incidence of delirium following open abdominal aortic aneurysm (AAA) surgery is significant, with incidence rates ranging from 12 to 33%. The occurrence of delirium on the surgical ward after intensive care unit (ICU) dismissal in AAA patients remains unclear. Differences in outcomes between a delirium on the ICU and a delirium on the surgical ward have not been previously investigated. An observational cohort study was conducted that included all patients treated electively for an abdominal aortic aneurysm (AAA) by open repair and patients undergoing emergency treatment for a ruptured AAA between 2013 and 2018. The diagnosis of delirium was verified by a psychiatrist or geriatrician using the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) criteria. Cox proportional hazards regression analysis was used to analyse 6- and 12-months survival rate.

Interventions

OTHERSurgery

All patients treated electively for an abdominal aortic aneurysm (AAA) by open repair and patients undergoing emergency treatment for a ruptured AAA between 2013 and 2018.

Sponsors

Amphia Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* All patients treated electively for an abdominal aortic aneurysm (AAA) by open repair and patients undergoing emergency treatment for a ruptured AAA between 2013 and 2018.

Exclusion criteria

* Patients that did not survive surgery * Patients that did not go to the intensive care unit postoperatively.

Design outcomes

Primary

MeasureTime frameDescription
the incidence of deliriumbetween january 2013 and december 2018The incidence of delirium on the ICU and on the ward

Secondary

MeasureTime frameDescription
mortality6 months and 12 monthsmortality divided by ICU delirium and ward delirium

Other

MeasureTime frameDescription
ReoperationsData on re-interventions, readmissions and survival were collected until February 2019.Reoperations within 30 days after surgery
Length of hospital stayData on re-interventions, readmissions and survival were collected until February 2019.Length of hospital stay in days
Discharge to a nursing homeData on re-interventions, readmissions and survival were collected until February 2019.Discharge to a nursing home
ComplicationsData on re-interventions, readmissions and survival were collected until February 2019.Complications within 30 days after surgery
Length of ICU stayData on re-interventions, readmissions and survival were collected until February 2019.Length of ICU stay in days

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026