Cancer Colon
Conditions
Keywords
cancer colon
Brief summary
Cancer Colon is one of the major public health problems worldwide. Complete eradication of the tumor with no recurrence or residual masses is a challenge which faces all the surgeons and medical staff all over the world. A lot of techniques were used to ensure 100 % eradication of the tumor and to cure the patients from cancer. Total Mesocolic Excision with Central Vessel Ligation is one of the recent techniques used for colon cancer surgeries. Here in the research the investigators answer the question of how this technique is superior and more beneficial in complete eradication of the tumor than the conventional surgery for colon cancer
Interventions
PROCEDURETotal Mesocolic Excision with Central Vessel Ligation
sharp dissection of the anatomical layers and the dissection of the visceral plane from the parietal one . In addition a central division of the feeding arteries at their origins is performed at the level of superior mesenteric artery for tumors of the right colon and at the level of inferior mesenteric artery or the aorta for tumors of the left colon .this allows for removal of the maximum number of lymph nodes possible.
PROCEDUREconventional surgery of cancer colon
removal of the tumor with no ligation of the vessel centrally or removal of the whole mesocolon
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* • Adult male and female Age of or above 18 years. * Tumor localization at the caecum, ascending colon, transverse colon, descending colon, sigmoid colon or rectosigmoid on preoperative endoscopy and radiographic imaging \[barium enema or computed tomography (CT)\] * No history of familial adenomatous polyposis, ulcerative colitis or Crohn's disease * Written informed consent
Exclusion criteria
* • Contraindications to major surgery and American Society of Anaesthesiologists (ASA) Physical Status scoring 4 which means extreme systemic disorders which have already become an eminent threat to life regardless of the type of treatment. * Infectious disease requiring treatment. * Pregnant women * Use of systemic steroids. * Severe pulmonary emphysema or pulmonary fibrosis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Lymph nodes harvest | Two years | Number of retrieved lymph nodes can be extracted by this technique |
Contacts
Primary ContactAmr E. Hassan, resident Doctor
Outcome results
None listed