Diabetes
Conditions
Keywords
hemoglobinA1c, serum fructosamine, glycemic control
Brief summary
Diabetes mellitus is associated with negative outcomes in patients undergoing surgery. Blood sugar levels are monitored by measuring a values that include but are not limited to hemoglobin A1c, capillary blood glucose, and fructosamine . This study is being done to investigate if there is an associated between these values and postsurgical outcomes.
Detailed description
This study aims to compare the predictive capacity of both fructosamine and HbA1c on preoperative basal glucose level, as well as adverse events (cardiovascular events, surgical site infection, and mortality) and length of post-anesthesia care unit (PACU) stay in both Type I and Type II diabetic patients. Secondary outcomes include length of anesthesia administration, an indicator of intraoperative complications, and perioperative glucose level.
Interventions
DIAGNOSTIC_TESTCapillary blood glucose blood draw
Capillary blood glucose (CBG), HbA1c, fructosamine, albumin, BUN, and creatinine values will be obtained from a blood draw as a standard of care
Sponsors
Ohio State University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
1. Male or female patients able to consent. 2. Patients with either Type I or Type II diabetes mellitus (DM) 3. Patients undergoing non-cardiac surgeries under general anesthesia 4. ≥ 18 years of age
Exclusion criteria
1. Inability to read, understand or sign the consent form 2. End-stage renal disease 3. Special populations (Incarcerated individuals, pregnant female patients)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| fasting capillary blood glucose level | 1 hour | Association between pre-operative HbA1c and fructosamine with pre-operative, fasting capillary blood glucose level measured the morning of surgery in preoperative holding area. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| hyperglycemia | 1 day | ii. Incidence of hyperglycemia, defined as CBG \> 180 mg/dL, during the perioperative period |
| infection | 1 day | Incidence of wound infection |
| wound healing | 1 day | Incidence of poor wound healing |
| hypoglycemia | 1 day | i. Incidence of hypoglycemia, defined as CBG \< 70 mg/dL, during the perioperative period |
| reoperation | 1 day | Incidence of reoperation procedure |
| LOS | 1 day | Length of PACU stay |
| delirium | 1 day | Incidence of post-operative delirium |
Countries
United States
Outcome results
None listed