Iron Supplementation in Hip/Knee Surgery

Sideral Forte in Prosthetic Hip and Knee Surgery

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04078880

Enrollment

Registered

2019-09-06

Start date

2018-12-04

Completion date

2020-01-01

Last updated

2023-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anemia, Hip Arthropathy, Iron Poor Blood, Knee Arthropathy, Orthopedic Disorder

Brief summary

Randomized controlled trial to evaluate the efficacy of oral iron supplementation in reducing the prevalence of preoperative anemia in a cohort of 82 patients undergoing elective prosthetic hip or knee surgery.

Interventions

DIETARY_SUPPLEMENTSucrosomial iron plus ascorbic acid

A number of 41 subjects are supplemented with 30 mg of iron plus 70 mg of ascorbic acid daily for 30+/-5 days before orthopedic surgery.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Males and females * ASA 1, 2, or 3 * No neuropsychiatric conditions * Acceptance of informed consent * Elective prosthetic hip or knee surgery

Exclusion criteria

* ASA 4 * Present or past neuropsychiatric conditions * Hip or knee revision surgery * Use of iron as dietary supplement * Known erythrocytosis * Incompatible hypersensitivities * Iron metabolism disorders * Lymphoproliferative disorders

Design outcomes

Primary

Measure	Time frame	Description
Change of blood hemoglobin levels	Baseline and 30 days +/- 5 days	CHange of hemoglobin concentration (g/dl) from baseline and after 30 days +/- 5 days

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026