Risk Factors for Potential Drug -Drug Interactions: Study in Surgical Intensive Care Unit -Zagazig University Hospitals.

Risk Factors for Potential Drug -Drug Interactions: Study in Surgical Intensive Care Unit -Zagazig University Hospitals

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04078620

Enrollment

120

Registered

2019-09-06

Start date

2018-06-15

Completion date

2019-04-20

Last updated

2019-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drug Interaction

Brief summary

Drug drug interactions is frequent in critically ill patients due to polypharmacy, different drug groups and prolonged ICU or hospital stay

Detailed description

This cross sectional study was conducted in Surgical ICU, zagazig University Hospital for 6months period. Demographic data (age, gender),clinical history data (main diagnosis, ICU stay in days, transfer from emergency room or other departments, on mechanical ventilation or not, state of consciousness

Interventions

DIAGNOSTIC_TESTSurvey for drug drug interactions on medscape and lexicomp applications

Survey for drug drug interactions on Medscape and Lexicomp interaction checker applications

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* all patients admitted to Surgical ICUs for six months period

Exclusion criteria

* less than one day admission to ICU,not completed data

Design outcomes

Primary

Measure	Time frame	Description
Severity of Drug interactions by Lexicomp interactions application	6months period	Lexicomp interactions classified As: A(no known interactions) B(no action needed) C(monitor therapy) D(consider therapy modification) X (avoid combination)
Severity of Drug interactions by Medescape interactions checker:	6months period	Interactions classified with Medescape interactions checker as :(contraindicated, serious use alternative, monitor closely,minor)

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026