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Gilles de la Tourette Syndrome (TS) and Seasonality

Gilles de la Tourette Syndrome (TS) and Seasonality: a Pilot Study

Status
Terminated
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04076852
Enrollment
39
Registered
2019-09-03
Start date
2018-04-06
Completion date
2019-05-31
Last updated
2023-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tourette Syndrome

Brief summary

This retrospective and prospective observational study intends to evaluate the correlation between seasons and the variation of the syndromic structure of the Tourette.

Interventions

According to clinical practice, the following questionnaires are administered: * Y-GTSS * Y-BOCS or cY-BOCS

Sponsors

I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
6 Years to 50 Years

Inclusion criteria

* Patients attending the Tourette Center since January 2012. * Males and females. * Age between 6 and 50 (completed). * Diagnosis of Tourette syndrome ascertained * Presence of a value equal to or greater than 15/40 of the Y-BOCS.

Exclusion criteria

* Presence of allergic pathology. * Presence of significant psychiatric symptoms, with the exception of those belonging to the Tourette Syndrome itself (eg ADHD, OCD)

Design outcomes

Primary

MeasureTime frameDescription
Change from baseline Y-GTSS score at 6 months.4, 8, 12 months.The primary objective is to investigate the correlation between seasons and different phenotypic variation through the administration of a specific questionnaire (Y-GTSS) and questions about the subjective perception of the ticcogenic variation.

Secondary

MeasureTime frameDescription
Change from baseline Y-BOCS score at 6 months.4, 8, 12 months.Secondary objective is to investigate the correlation between seasons and variation of severity of obsessive-compulsive disorder (OCD) through the administration of Y-BOCS, a questionnaire indicated to evaluate the severity of obsessive-compulsive disorder.

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026