OCT-angiography as a Pronostic Marker for Visual Impairment in Patients Undergoing Neurosurgery for Compressive Macroadenoma : a Prospective Study.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04074642

Acronym

FIRST

Enrollment

Registered

2019-08-30

Start date

2019-11-14

Completion date

2023-02-22

Last updated

2026-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pituitary Adenoma

Keywords

macroadenoma

Brief summary

The aim of the study is to assess accurancy of OCT angiography as a pronostic marker for patients undergoing neurosurgery for compressiver macroadenoma as compared with visual acuity, visual field and OCT.

Interventions

PROCEDURENeurosurgery

adenoma removal

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* pituitary compressive adenoma (for experimental group) * pituitary non compressive adenoma

Exclusion criteria

* retinian disease * amblyopia * parkinson disease * pregnant woman

Design outcomes

Primary

Measure	Time frame	Description
change of middle deviation	before surgery (= inclusion), 4 months after surgery and 10 months after surgery	visual field evolution assessed by Middle deviation
Change of visual function index	before surgery (= inclusion), 4 months after surgery and 10 months after surgery	visual field evolution assessed by visual function index

Countries

France

Contacts

PRINCIPAL_INVESTIGATORARNAUD MARTEL

ophtalmology department, Nice University Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 25, 2026