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Prevalence of Sonographic Abnormalities of Joints and Entheses in Psoriasis Patients With or Without Musculoskeletal Complains

Prevalence of Sonographic Abnormalities of Joints and Entheses in Patients With Psoriasis With or Without Musculoskeletal Complains

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04074070
Acronym
EchoPso
Enrollment
25
Registered
2019-08-29
Start date
2020-02-18
Completion date
2020-09-30
Last updated
2023-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis

Keywords

psoriasis, psoriatic arthritis, ultrasound

Brief summary

The objectives of this study are: * to estimate the prevalence and severity of inflammatory (synovitis, tenosynovitis, enthesitis, dactylitis) and structural (erosions, osteophytes, enthesophytes, cortical irregularities ) ultrasound lesions in psoriasis patients with or without related musculoskeletal symptoms; * to compare them to healthy subjects or patients suffering from rheumatoid arthritis and osteoarthritis.

Interventions

OTHERUltrasound examination

Ultrasound examination of joints, tendons and entheses.

Sponsors

Assistance Publique - Hôpitaux de Paris
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Age ≥ 18 years; * Psoriasis diagnosed by a dermatologist; * Able to participate in the study; * Informed consent signed.

Exclusion criteria

\- Chronic disease likely to cause musculoskeletal symptoms (connective tissue diseases, inflammatory bowel diseases, overload disorders, crystal related arthritis, septic arthritis...).

Design outcomes

Primary

MeasureTime frameDescription
synovitisthrough study completion, an average of 1 yearNumber and percentage, N (%) of patients with at least one synovitis.
enthesitisthrough study completion, an average of 1 yearN (%) of patients with at least one ultrasound enthesitis.
joint erosionthrough study completion, an average of 1 yearN (%) of patients with at least one joint erosion.
osteophyte/ cortical irregularitythrough study completion, an average of 1 yearN (%) of patients with at least one osteophyte/ cortical irregularity.
enthesophytethrough study completion, an average of 1 yearN (%) of patients with at least one enthesophyte.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026