Psoriasis
Conditions
Keywords
psoriasis, psoriatic arthritis, ultrasound
Brief summary
The objectives of this study are: * to estimate the prevalence and severity of inflammatory (synovitis, tenosynovitis, enthesitis, dactylitis) and structural (erosions, osteophytes, enthesophytes, cortical irregularities ) ultrasound lesions in psoriasis patients with or without related musculoskeletal symptoms; * to compare them to healthy subjects or patients suffering from rheumatoid arthritis and osteoarthritis.
Interventions
Ultrasound examination of joints, tendons and entheses.
Sponsors
Study design
Eligibility
Inclusion criteria
* Age ≥ 18 years; * Psoriasis diagnosed by a dermatologist; * Able to participate in the study; * Informed consent signed.
Exclusion criteria
\- Chronic disease likely to cause musculoskeletal symptoms (connective tissue diseases, inflammatory bowel diseases, overload disorders, crystal related arthritis, septic arthritis...).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| synovitis | through study completion, an average of 1 year | Number and percentage, N (%) of patients with at least one synovitis. |
| enthesitis | through study completion, an average of 1 year | N (%) of patients with at least one ultrasound enthesitis. |
| joint erosion | through study completion, an average of 1 year | N (%) of patients with at least one joint erosion. |
| osteophyte/ cortical irregularity | through study completion, an average of 1 year | N (%) of patients with at least one osteophyte/ cortical irregularity. |
| enthesophyte | through study completion, an average of 1 year | N (%) of patients with at least one enthesophyte. |
Countries
France