Sarcopenia
Conditions
Brief summary
In the subgroup of patients with sarcopenia, regardless of their body mass index, we want to verify the real impact of nutritional supplements with branched chain amino acids on the standard treatment based on nutritional intervention and physical exercise.
Interventions
DIETARY_SUPPLEMENTBranched chain amino acids (BRCA)
They were with BRCA during the day apart of following the standard recommendations
Sponsors
Puerta de Hierro University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Cirrhotic patients with sarcopenia in abdominal CT.
Exclusion criteria
* chronic renal failure or being on hemodialysis * active hepatitis B or C virus infection * active alcohol abuse * coinfection with human immunodeficiency virus * renal or previous liver transplantation * history of neoplasia requiring chemotherapy or radiotherapy * hepatocellular carcinoma outside of Milan criteria * TIPs * unwillingness to participate in the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of muscle mass in patients with sarcopenia | 12 weeks | To assess whether to add to dietary and physical activity recommendations, nutritional supplements with BRCA under usual clinical conditions can lead to a greater change of muscle mass in patients with sarcopenia |
Countries
Spain
Outcome results
None listed