Apical Periodontitis
Conditions
Keywords
Biomaterials, irrigation protocol, pariapical healing
Brief summary
The purpose is to investigate influence of bioceramic filling of the root canal and photodynamic therapy on periapical healing and development of postoperative pain after endodontic retreatment. Patients are divided into two main groups and each of the group is divided into two subgroups. Main groups are patients receiving photodynamic therapy and patients receiving passive ultrasonic irrigation. Each of the main group is divided by the root canal filling material on the AH+ group and BioRoot group.
Detailed description
Clinical trial will be conducted in Dental clinic Zagreb. Patients will be chosen for this randomized prospective trials from the everyday patients referred by general dentist for endodontic retreatment. In the research will be included only patients with symptoms of chronic apical periodontitis and previous endodontic treatment. It includes teeth sensitive to palpation, percussion or visible sinus tract or swelling and asymptomatic inadequate endodontic filling. Patients that are immunocompromised, pregnant women, teeth with pocket depth bigger then 3mm, teeth with signs of vertical root fracture, teeth that are impossible to restore are excluded from research. Every patient will be assigned to one group and one subgroup using wheeldecide programme. Patients will not be aware what group or subgroup they are assigned. endodontic retreatment will be conducted by one specialist in endodontics. Therapy is single visit retreatment.
Interventions
DRUGBioRoot
Influence of biomaterial BioRoot on periapical healing
Sponsors
University of Zagreb
Medical Innovation Center Wroclaw
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Intervention model description
Each of the two main groups are divided to two subgroups.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patients with symptoms of periapical disease after endodontic treatment, * teeth sensitive to percussion and palpation, * teeth with present sinus tract and * asymptomatic teeth with radiologically inadequate root canal filling.
Exclusion criteria
* Immunocompromised patients, * pregnancy, * teeth with signs of vertical root fracture, * teeth that can't be restored, * antibiotic usage within last month, * teeth with acute apical abscess
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in volume of periapical lesion | 1 year | Volumetric change of size of periapical lesion depending of the root canal filling material and the use of photodynamic therapy at the end of chemomechanical preparation. |
| Level of postoperative pain after endodontic treatment | 7 days day after day monitoring of the level of pain. | After endodontic treatment receives questionaire with day - by - day monitoring of the level of pain on the scale from 0 (no pain) to 10 (sever pain) |
Countries
Croatia
Outcome results
None listed