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Microbial Composition of Breast Milk Collected From Healthy Turkish Women

Evaluation of Microbial Composition in Human Milk From Healthy Women in the Turkish Population: an Observational Cross-sectional Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04072627
Enrollment
20
Registered
2019-08-28
Start date
2018-05-05
Completion date
2019-07-05
Last updated
2019-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Microbial Community in Breast Milk

Keywords

breast milk, microbiota

Brief summary

Breast milk is an optimal source of nutrients for newborns as well as a potential source of bacteria for the intestinal microbiota. However, there are limited number of studies evaluating the relationship between maternal nutrition, breast milk and neonatal intestinal microbiota.

Detailed description

The study was conducted on a total of 20 healthy women following at Obstetrics and Gynecology Department of Gülhane Education and Research Hospital in Ankara Health Sciences University. Sociodemographic characteristics, anthropometric measurements, breastfeeding characteristics were evaluated in the third trimester of the women who underwent routine prenatal care. Breast milk samples were obtained at 16.day postpartum during lactation.

Interventions

None listed

Sponsors

Turkish Society of Clinical Enteral and Parenteral Nutrition
CollaboratorOTHER
Hacettepe University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
20 Years to 31 Years
Healthy volunteers
Yes

Inclusion criteria

* Singleton pregnancy * Age 19-35 years * At weeks of 30-36 gestation * No history of acute or chronic diseases * Term delivery

Exclusion criteria

* Alcohol use * Smoking * Gestational diabetes * Type 1 and 2 diabetes * Preeclampsia * Polycystic ovary * Syndrome * Thyroid and parathyroid disease * Metabolic bone or kidney disease * Abnormal liver function * Multiple pregnancy * Premature and postmature labor * Having chemotherapy * Taking drugs such as antibiotics and probiotics

Design outcomes

Primary

MeasureTime frameDescription
Microbial abundance and diversityat 16 day postpartumThe microbial composition of the breast milk samples was determined by 16S rRNA (ribosomal ribonucleic acid) gene sequencing analysis.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026