Stroke Survival in Municipalities: Impact of Geographic Proximity to First- and Second-degree Relatives

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04072120

Enrollment

7400000

Registered

2019-08-28

Start date

2019-08-15

Completion date

2022-08-14

Last updated

2020-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Keywords

Stroke, Post-acute stroke, Geographical proximity, Family, Relatives, Survival analysis

Brief summary

Our key objective will be to investigate if geographic proximity to first- and second-degree relatives has an influence on post-acute stroke survival and use of health and social services. We will also model and map spatial variation in stroke and cardiovascular disease (CVD) incidence and mortality and see if some of the variation is due to spatial clustering of familial risk. The study will use innovative approaches to large-scale registry and survey data and statistical analysis on the full Norwegian population. We will integrate multigenerational and geographical information. This will enable us to assess key determinants on stroke survival and use of health and social care at municipality level.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

45 Years to No maximum

Healthy volunteers

Inclusion criteria

* Norwegian citizens aged 45 and above 1.1.1994 - 31.12. 2009 and had stroke events * Those who attend a cardiovascular health survey who later developed stroke. * All Norwegians born in the period 1 January 1940 to 31 December 1959 who survived to 1991 * Norwegian citizens aged 45 and above 1.1.2016 and had stroke events

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
R1- Mortality	Mortality follow-up from 1.1.1994 to 31.12.2014	Mortality of Norwegian citizens aged 45 and above 1.1.1994 - 31.12. 2009
R2- Mortality	Mortality follow-up from 1991-2014.	Mortality of all Norwegians born in the period 1 January 1940 to 31 December 1959 who survived to 1991
R3- Stroke events	Stroke events registered in the Patient registry after 2016, (possibly until 2019)	Norwegian citizens aged 45 and above 1.1.2016

Countries

Norway

Outcome results