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Prevention of Conversion in Posterior Retroperitoneal Adrenalectomy by Measuring Preoperative Anatomical Conditions

Prevention of Conversion in Posterior Retroperitoneal Adrenalectomy by Measuring Preoperative Anatomical Conditions on Cross-sectional Imaging (CT or MRI)

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04071561
Enrollment
14
Registered
2019-08-28
Start date
2018-11-19
Completion date
2019-05-31
Last updated
2019-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adrenal Hyperplasia, Adrenal Mass, Adrenal Metastases, Adrenal Tumor, Conn Adenoma, Pheochromocytoma

Keywords

Adrenalectomy, Minimally invasive surgery, Posterior Retroperitoneoscopic adrenalectomy, Retroperitoneal fat mass

Brief summary

With our retrospective study the investigators show the limitations of the posterior retroperitoneal adrenalectomy by analyzing anatomical parameters. The investigators compared the data from one patient who underwent a conversion with 13 patients without a conversion. Furthermore, they explored the influence of these parameters on the operation time and excluded the patient who had a conversion from this analysis. The investigators hypothesize that by determining anatomical characteristics on cross-sectional imaging (CT or MRI), they can show the limitations of the posterior retroperitoneal adrenalectomy to prevent patients from being converted to lateral transperitoneal adrenalectomy.

Detailed description

Minimally invasive adrenalectomy has become the gold standard for the surgical treatment of small, benign adrenal lesions. In addition to the common laparoscopic lateral transperitoneal adrenalectomy, the posterior retroperitoneal adrenalectomy is becoming increasingly important. To date, there is no consensus regarding the preferred approach in the resection of benign adrenal tumors. A comprehensive adrenal tumor program should be able to offer both options, however, patient selection criteria for a given approach have not yet been defined. The choice between lateral transperitoneal adrenalectomy and posterior retroperitoneal adrenalectomy is relevant for patients with unilateral tumors \< 6-7 cm and without previous abdominal surgery. The aim of this study was to determine the limits of posterior retroperitoneal adrenalectomy using anatomical parameters to enable the preferred access to be chosen preoperatively to prevent conversion. In addition, the investigators describe the relationship between these parameters and the operation time to find a measure of the degree of technical difficulty.

Interventions

OTHERPosterior retroperitoneal adrenalectomy (PRA)

Minimally invasive adrenalectomy procedure

OTHERLateral transperitoneal adrenalectomy (LTA)

During posterior retroperitoneal adrenalectomy, the failure to progress or the difficulty of creating or maintaining a pneumoperitoneum are reasons why conversion occurs.

Sponsors

Kantonsspital Aarau
CollaboratorOTHER
University of Basel
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients whose adrenal gland was removed with retroperitoneal access * Operation was between 01.07.2016 and 31.12.2018 * Operation was at the Kantonsspital Aarau

Exclusion criteria

* Patients with multivisceral resection

Design outcomes

Primary

MeasureTime frameDescription
Operative timeThe data were collected between 19.11.2018 and 04.02.2019.Duration of adrenalectomy. Data were extracted and analyzed from the hospital information system.
Longitudinal distance between the superior border of the adrenal gland to the 12th rib tip.The measurement was performed in the period from 19.11.2018 - 04.02.2019.Measurement of preoperative anatomical conditions on cross- sectional imaging (CT or MRI). Longitudinal distance between the superior border of the adrenal gland to the 12th rib tip, mm.
Longitudinal distance between the 12th rib and the iliac crestThe measurement was performed in the period from 19.11.2018 - 04.02.2019.Measurement of preoperative anatomical conditions on cross- sectional imaging (CT or MRI). Longitudinal distance between the 12th rib and the iliac crest, mm.
Sagittal thickness of the subcutaneous layer above the 12th rib tipThe measurement was performed in the period from 19.11.2018 - 04.02.2019.Measurement of preoperative anatomical conditions on cross- sectional imaging (CT or MRI). Sagittal thickness of the subcutaneous layer above the 12th rib tip, mm.
Sagittal thickness of the subcutaneous layer above the iliac crestThe measurement was performed in the period from 19.11.2018 - 04.02.2019.Measurement of preoperative anatomical conditions on cross- sectional imaging (CT or MRI). Sagittal thickness of the subcutaneous layer above the iliac crest, mm.
Thickness of the subcutaneous layer above the 12th rib tipThe measurement was performed in the period from 19.11.2018 - 04.02.2019.Measurement of preoperative anatomical conditions on cross- sectional imaging (CT or MRI). Thickness of the subcutaneous layer above the 12th rib tip, measured on the straight line to the center of gravity, mm.
Sagittal thickness of the subcutaneous layer between the center of gravity and the lateral border of the bodyThe measurement was performed in the period from 19.11.2018 - 04.02.2019.Measurement of preoperative anatomical conditions on cross- sectional imaging (CT or MRI). Sagittal thickness of the subcutaneous layer between the center of gravity and the lateral border of the body, measured at the level of the 12th rib tip, mm.
Tumor sizeThe measurement was performed in the period from 19.11.2018 - 04.02.2019.Measurement of preoperative anatomical conditions on cross- sectional imaging (CT or MRI). Tumor size, cm.
Sagittal distance between the dorsal border of the adrenal gland and the 12th rib tipThe measurement was performed in the period from 19.11.2018 - 04.02.2019.Measurement of preoperative anatomical conditions on cross- sectional imaging (CT or MRI). Sagittal distance between the dorsal border of the adrenal gland and the 12th rib tip, mm.
Thickness of retroperitoneal fatThe measurement was performed in the period from 19.11.2018 - 04.02.2019.Measurement of preoperative anatomical conditions on cross- sectional imaging (CT or MRI). Defined as the largest distance between the kidney parenchyma and the posterior abdominal wall at the level where the renal vein joins the vena cava inferior.
Posterior Adiposity IndexThe measurement of the parameter from the cross-sectional image was performed in the period from 19.11.2018 - 04.02.2019.Measurement of preoperative anatomical conditions on cross- sectional imaging (CT or MRI). Distance from skin to renal parenchyma through the 12th rib tip. The larger the distance, the larger the index. The scale ranges are open.
Longitudinal distance between the upper pole of the kidney and the inferior border of the adrenal gland.The measurement was performed in the period from 19.11.2018 - 04.02.2019.Measurement of preoperative anatomical conditions on cross- sectional imaging (CT or MRI). Longitudinal distance between the upper pole of the kidney and the inferior border of the adrenal gland, mm.

Secondary

MeasureTime frameDescription
Body-Mass-IndexThe data were collected between 19.11.2018 and 04.02.2019.Value derived from the mass (weight) and height of a person. Data were extracted and analyzed from the hospital information system.
Previously performed abdominal surgeries taken from the hospital information systemThe data were collected between 19.11.2018 and 04.02.2019.Previous abdominal operations with opening of the abdominal cavity which give an indication of adhesions.Data were extracted and analyzed from the hospital information system.
AgeThe data were collected between 19.11.2018 and 04.02.2019.Age at adrenalectomy. Data were extracted and analyzed from the hospital information system.
SexThe data were collected between 19.11.2018 and 04.02.2019.Female or Male
Histological diagnosis of the sample from the adrenalectomyThe data were collected between 19.11.2018 and 04.02.2019.Histological evaluation. Data were extracted and analyzed from the hospital information system.
ImagingThe data were collected between 19.11.2018 and 04.02.2019.CT or MRI
The side of the adrenal gland that was removedThe data were collected between 19.11.2018 and 04.02.2019.Side of the removed adrenal gland (left, right, bilateral). Data were extracted and analyzed from the hospital information system.

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026