EEG Monitoring in the Emergency Department

Observational Study of EEG Monitoring of Patients in the Emergency Department

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04070521

Enrollment

Registered

2019-08-28

Start date

2019-09-06

Completion date

2024-10-31

Last updated

2023-08-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol Abuse, Drug Overdose, Substance Abuse

Keywords

Electroencephalogram, Opioids, Alcohol, Benzodiazepines, Alpha-2 agonists, Propofol, Ketamine, Marijuana, Neuromechanisms of intoxicants

Brief summary

This study seeks to investigate whether drug effects in suspected overdose patients could be identified using the electroencephalogram (EEG). From previous work it is known that different classes of anesthetic drugs have specific EEG signatures related to the drug mechanisms. Many of the drugs of abuse that are frequently encountered in overdose patients are similar or identical to anesthetic drugs. The hypothesis for this study is that the EEG could be used to characterize the brain effects of intoxicants using EEG in the ED setting. Such monitoring could one day help clinicians and first responders at the point-of-care make more informed decisions to improve the care of overdose patients.

Interventions

OTHERObservational EEG Monitoring

Subjects will be monitored with electroencephalogram (EEG) after arriving to the Emergency Department with suspected overdose

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult patients aged 18 years and older who present to the ED with suspected use of a potential drug of abuse

Exclusion criteria

* Hemodynamic instability or other acute medical condition for which the primary treating team does not thing it would be appropriate or safe for the study staff to approach the patient * The patient has an overt head trauma or deformity of the face which would preclude application of the forehead EEG monitoring lead * The patient has dermatological issues or skin conditions on the forehead * The patient has known dementia and/or mental impairment * The patient is a prisoner * The patient is an employee or student at one of the study sites.

Design outcomes

Primary

Measure	Time frame	Description
Electroencephalogram (EEG)	24 hours	Subject EEG activity following arrival to Emergency Department with suspected overdose, including EEG waveform, spectrum, spectrogram, and power in the slow (0.1-1 Hz), delta (1 to 4 Hz), theta (4 to 8 Hz), alpha (8 to 12 Hz), beta (12 to 25 Hz), and gamma (25 to 70 Hz) bands.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026