Transcutaneous Electrical Nerve Stimulation for Tissues Perfusion

Effect of Transcutaneous Electrical Nerve Stimulation on Tissue Perfusion for the Critically Ill Patient

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04069871

Enrollment

Registered

2019-08-28

Start date

2019-10-15

Completion date

2020-10-06

Last updated

2020-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Function Disorder, Critical Illness, Critical Illness Myopathy

Brief summary

The aim of this study is to determine the effect of transcutaneous electrical nerve stimulation in mechanically ventilated patients on the lower limb and renal tissue perfusion.

Interventions

DEVICEtrans-cutaneous electrical nerve stimulation.

• Patients assigned to the EMS group received daily EMS sessions of both lower extremities starting from the second day for 5days.

DEVICESham TENS

Patients in the control group will receive sham TENS.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Recently intubated patient. * Adult and both gender. * Hemodynamic stability

Exclusion criteria

* Vascular diseases * Diabetic patients * Patients who receive vasoactive drugs * Patients with varicose vein * Systemic scoliosis

Design outcomes

Primary

Measure	Time frame	Description
tissue perfusion of the lower limb.	5 ICU days	capillary refill time
Renal perfusion	5 ICU days	quantitative assessment of neutrophil gelatinase-associated lipocalin

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026